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Denzel Perryman MLB | LAC
Chargers' Denzel Perryman: Progressing in recovery
Head coach Jim Harbaugh said Wednesday that Perryman (undisclosed) is "close" to returning from injured reserve, Alex Insdorf of BoltBeat.com reports.
Harbaugh added that Perryman isn't quite ready to return to practice, and given that the veteran linebacker's 21-day practice window has yet to open, he's probably not available for Sunday's game against the Rams. Perryman landed on IR on Sept. 1 due to an undisclosed injury that he may have picked up toward the tail end of training camp.
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Karon Prunty CB | NE
Patriots' Karon Prunty: Full participant Wednesday
Prunty (hamstring) was a full participant in Wednesday's practice.
Prunty logged full practice participation for the first time since sustaining his hamstring injury during the Patriots' Week 4 win over the Bills. If the cornerback can continue to log full sessions through Friday's practice, he should be all set to suit up for Sunday's game against the Dolphins as a meaningful depth addition to the Patriots' secondary.
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Deane Leonard CB | LAC
Chargers' Deane Leonard: Doesn't practice due to concussion
Leonard (concussion) did not participate in Wednesday's practice, Alex Insdorf of BoltBeat.com reports.
It is unclear when Leonard sustained his concussion, as the Chargers were on bye in Week 7. The depth cornerback has enterted the NFL's five-step concussion protocol and will not be able to suit up for full-contact activities until he is cleared by an independent neurologist.
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Torricelli Simpkins III G | CAR
Panthers' Torricelli Simpkins: Ruled out for TNF
Simpkins (ankle) has been ruled out for Thursday's game against the Packers.
Simpkins was unable to practice all week due to an ankle injury, which he likely picked up during Sunday's 43-13 loss to the Buccaneers. With Damien Lewis (knee) also ruled out, Corey Bullock will likely start at left guard in Thursday night's game. Simpkins' next chance to suit up is Week 9 against the Broncos on Sunday, Nov. 8.
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Damien Lewis G | CAR
Panthers' Damien Lewis: Won't play against Green Bay
Lewis (knee) has been ruled out for Thursday's game against the Packers.
Lewis likely picked up the injury during Sunday's 43-13 loss to the Buccaneers. He was unable to practice all week due to his injury, and with Torricelli Simpkins (ankle) also ruled out, Corey Bullock figures to step into the starting role at left guard. Lewis' next chance to play is Week 9 against the Broncos on Sunday, Nov. 8.
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Laremy Tunsil OT | WAS
Commanders' Laremy Tunsil: Remains on-track with recovery
Tunsil (triceps) could potentially return late in the season, Nicki Jhabvala of The Athletic reports.
Tunsil has another check-up in a few weeks, which will give the Commanders a better sense of a potential return timeline in 2026. The offensive tackle is still a ways away from football, but the consistency in his recovery process leaves the door open for an eventual return.
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Joseph Ossai DE | NYJ
Jets' Joseph Ossai: Doesn't practice Wednesday
Ossai (ankle) didn't participate in the Jets' practice Wednesday, Rich Cimini of ESPN.com reports.
Ossai is unlikely to play in Sunday's matchup versus the Raiders and is currently considered week-to-week due to an ankle injury he sustained during the Week 5 win over the Browns. Will McDonald and Nate Lynn should continue to see increased playing time in Ossai's absence.
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Nolan Smith LB | PHI
Eagles' Nolan Smith: Back at practice Wednesday
Smith (concussion) was a limited participant in Wednesday's practice.
Smith entered the league's concussion protocol against the Panthers in Week 6. He did not practice during Week 7 prep, so his limited session Wednesday indicates that he is progressing in his recovery. He would need to be cleared from the league's protocol by an independent neurologist in order to be available for Sunday's game against the Commanders.
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Tytus Howard OT | CLE
Browns' Tytus Howard: Doesn't practice Wednesday
Howard (concussion) didn't participate in Cleveland's practice Wednesday.
Howard is in the league's concussion protocol after exiting Sunday's win over the Titans due to a concussion. Dawand Jones is in line to start at right tackle if Howard is unable to clear the concussion protocol before Sunday's matchup versus the Steelers.
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Quinnen Williams DT | DAL
Cowboys' Quinnen Williams: Limited in practice Wednesday
Williams (hamstring) was a limited participant in Wednesday's practice, Jon Machota of The Athletic reports.
Williams is dealing with a hamstring injury he likely sustained in the Cowboys' Week 7 win over the Eagles on Monday. The defensive lineman will likely need to upgrade to a full participant by Friday's practice to avoid any injury designation ahead of Sunday's game against the Cardinals.