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Omarion Hampton RB | LAC
Chargers' Omarion Hampton: Back at practice, limited Wednesday
Hampton (ankle) was limited in his return to practice Wednesday, Eric Smith of the Chargers' official site reports.
Hampton, who last saw game action in Week 5 when he sustained a fractured ankle, was designated to return from IR on Tuesday, which has the running back trending in the right direction ahead of Sunday's game against the Raiders. Per Smith, Hampton's Week 13 availability presumably hinges on how he fares this week at practice, but for his part, the 2025 first-rounder is anxious to return to the lineup. "They haven't told me yet, but I'm waiting to find out. Whatever my doc says," Hampton noted Wednesday. "I want to, for sure. But it's whatever the doc says." In any case, in order for Hampton to be available versus Las Vegas, he'd need to be activated from IR by Saturday afternoon.
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Yetur Gross-Matos DE | SF
49ers' Yetur Gross-Matos: Will remain on IR
Head coach Kyle Shanahan relayed Wednesday that the 49ers will not designate Gross-Matos (knee) to return from injured reserve, Matt Maiocco of NBC Sports Bay Area reports.
Gross-Matos missed three games in October before landing on injured reserve Nov. 1 due to a hip injury. This Sunday's game against the Browns will mark his eighth-straight missed game, and with the 49ers on a bye Week 14, his next opportunity to play is Week 15 against the Titans on Sunday, Dec. 14.
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Rylie Mills DT | SEA
Seahawks' Rylie Mills: Designated to return
The Seahawks designated Mills (knee) to return from the reserve/non-football injury list Wednesday, Brady Henderson of ESPN reports.
Mills has been on the NFI list since July but is now one step closer to making his return. The team will now have 21 days to officially activate the rookie fifth-round pick, who will look to make his NFL debut once fully healthy.
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Michael Mayer TE | LV
Raiders' Michael Mayer: Misses practice Wednesday
Mayer (ankle) didn't practice Wednesday.
Mayer exited this past Sunday's loss to the Browns after logging 13 snaps on offense, and the tight end's DNP on Wednesday clouds his Week 13 status. Mayer now has two more chances to practice before the Raiders unveil their final injury designations ahead of Sunday's game against the Chargers.
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Cam Akers RB | SEA
Seahawks' Cam Akers: Signs with Seattle
The Seahawks signed Akers on Wednesday, Brady Henderson of ESPN reports.
Akers is headed to Seattle after being cut from Minnesota's practice squad last week. The 26-year-old carried the ball five times for 19 yards in three appearances with the Vikings. He should serve as the Seahawks' No. 3 running back for Sunday's matchup against his former team, as George Holani is doubtful with a hamstring injury.
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Tre Tucker WR | LV
Raiders' Tre Tucker: Logs limited practice Wednesday
Tucker (knee) was limited at practice Wednesday.
Tucker was on the field for 95 percent of the Raiders' snaps on offense in this past Sunday's 24-10 loss to the Browns en route to recording three catches on a team-high 10 targets for 28 yards. Following a limited practice listing Wednesday, the wideout now has two more chances to upgrade his participation level before the Raiders post their Week 13 injury designations Friday.
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Ashton Jeanty RB | LV
Raiders' Ashton Jeanty: Not listed on injury report
Jeanty (ankle) isn't listed on the Raiders' Week 13 injury report.
Field Yates of ESPN previously noted that Jeanty emerged from Week 12 action with an ankle injury that he sustained late in Sunday's 24-10 loss to the Browns, a game in which the running back recorded an 81 percent snap share while carrying 17 times for 50 yards and catching all eight of his targets for 58 yards and a TD. On Monday, coach Pete Carroll indicated that he didn't believe Jeanty's ankle issue was anything severe, a notion that has now been confirmed by the fact that the Raiders' lead back is working without restrictions ahead of this weekend's game against the Chargers.
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Alex Highsmith LB | PIT
Steelers' Alex Highsmith: Limited in Wednesday's practice
Highsmith (pectoral) was a limited participant in Pittsburgh's practice Wednesday, Brooke Pryor of ESPN reports.
Highsmith has missed the past two games with a pectoral injury but managed to practice Wednesday, albeit in a limited capacity. The 28-year-old will look to make his return to the lineup during Sunday's matchup versus the Bills.
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Cameron Heyward DE | PIT
Steelers' Cameron Heyward: Limited participant in practice
Heyward (ankle) was a limited participant in Pittsburgh's practice Wednesday, Brooke Pryor of ESPN reports.
Heyward's practice status was likely precautionary, as he was also limited in practice last week before eventually playing in the team's Week 12 loss versus Chicago. The 36-year-old has recorded just 1.5 sacks so far this season but will look to be more productive Sunday versus the Bills.
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Joey Porter Jr. CB | PIT
Steelers' Joey Porter: Limited in practice
Porter (hip) was a limited participant in Pittsburgh's practice Wednesday, Brooke Pryor of ESPN reports.
Porter's status comes as no surprise, as Mike Tomlin previously announced he would be limited in practice throughout the week. However, the 25-year-old is still expected to be good to go for Sunday's game versus Buffalo.