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Jaxon Smith-Njigba WR | SEA
Seahawks' Jaxon Smith-Njigba: In clear for Week 6
Smith-Njigba (ankle) practiced fully Wednesday and doesn't have a designation for Thursday's game in Denver, Curtis Crabtree of Fox 13 Seattle reports.
The Seahawks listed Smith-Njigba as limited on practice estimates Monday and Tuesday due to an ankle issue, but it didn't hold him back Wednesday, and he thus is in the clear for Week 6 action. He'll be looking to build upon the massive 37-583-7 line on 50 targets that he's amassed through five contests to start the campaign.
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Quentin Johnston WR | LAC
Chargers' Quentin Johnston: Gets in limited session
Johnston (chest) was listed as a limited participant on Wednesday's injury report.
A chest injury kept Johnston off the field for Week 5, but he was able to get some work in Wednesday. Fellow pass catchers Ladd McConkey (foot) and Tre' Harris (hamstring) are also banged up -- the latter did not practice Wednesday -- so it remains to be seen what the Los Angeles receiver room will look like Sunday against the Chiefs.
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DeVonta Smith WR | PHI
Eagles' DeVonta Smith: DNP on Wednesday
Smith (hamstring) was a non-participant at Wednesday's practice.
While Smith remained sidelined from on-field work, he was spotted working on a JUGS machine during the open portion of Wednesday's session, per Olivia Reiner of The Philadelphia Inquirer. Smith has missed the last two games due to a hamstring issue and may be trending toward a third absence if he isn't able to get back on the practice field by Friday.
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Grant Calcaterra TE | PHI
Eagles' Grant Calcaterra: Practice window opened
The Eagles opened the 21-day practice window for Calcaterra (back) on Wednesday.
Calcaterra has yet to play this season. He will have 21 days to be added to the 53-man roster. If not, Calcaterra will miss the remainder of the 2026 campaign.
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Ladd McConkey WR | LAC
Chargers' Ladd McConkey: Listed as limited participant
McConkey (foot) was listed as a limited participant on Wednesday's injury report.
Head coach Jim Harbaugh revealed earlier Wednesday that McConkey would get some work in, and he was officially marked down with a limited tag. It's too early to tell if McConkey will take the field in Week 6, but his participation in Wednesday's session bodes well for his chances of doing so.
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Saquon Barkley RB | PHI
Eagles' Saquon Barkley: Sidelined at Wednesday's practice
Barkley (hamstring) officially didn't practice Wednesday.
Barkley has yet to mix into drills since suffering a right hamstring injury in the early stages of the Eagles' Week 4 loss to the Rams. Head coach Nick Sirianni expressed hope Monday that Barkley will return to action Sunday against the Panthers, suggesting it's possible he gets back on the practice field by Friday. Until that happens, though, Barkley likely is trending toward another absence in Week 6, which would leave Philadelphia's backfield in the hands of Dameon Pierce and Carson Steele with Will Shipley (foot) set for a multi-week stay on the sideline.
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Rashod Bateman WR | BAL
Ravens' Rashod Bateman: Limited Wednesday, should play Sunday
Bateman (shoulder) was a limited participant in Wednesday's practice.
Per Cordell Woodland of 105.7 The Fan Baltimore, Bateman was spotted with a non-contact jersey Wednesday and was able to fit in some on-field work behind closed doors after not working out with the team during the open portion of the session. Though the wideout is on the injury report for a second straight week on account of the shoulder issue, head coach Jesse Minter said after Wednesday's practice that Bateman "should be fine" for Sunday's game against the Browns, according to Jamison Hensley of ESPN.com.
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Zach Charbonnet RB | SEA
Seahawks' Zach Charbonnet: Won't return in Week 6
Charbonnet (knee) has been ruled out for Thursday's game at Denver, Corbin K. Smith of EmeraldCitySpectrum.com reports.
The Seahawks opened Charbonnet's practice window to return from the reserve/PUP list on Oct. 1, but he's yet to log anything more than a limited practice since then. The team now has until next Thursday, Oct. 22 to activate him, or else he'll be required to miss the rest of the season by rule. Of course, Seattle does expect Charbonnet to play this season, so even if he isn't ready to play in Week 7, the move will be made next week. In the meantime, Emanuel Wilson will continue to lead the backfield, with George Holani backing him up.
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T.J. Edwards LB | CHI
Bears' T.J. Edwards: Facing multi-week absence
Edwards (hamstring) is considered week-to-week, Adam Hoge of AllCHGO.com reports.
Edwards suffered a hamstring injury in Sunday's loss to the Packers and did not return. While he hasn't officially been ruled out for the Week 6 meeting with the Falcons, he's not expected to be on the field. If that's the case, D'Marco Jackson and Noah Sewell are expected to be more involved.