Orioles starter Jason Hammel endured another rough outing as he picked up his second loss of the season Friday night against the Rays.

Hammel (5-2), who made his ninth start of the season, surrendered a three-run home run to Kelly Johnson in the third inning. The right-hander was charged with a season-high seven runs and 10 hits in 4 2/3 innings of work. He struck out four and walked two in a 12-10 defeat.

Hammel suffered his first loss since April 7. His ERA has increased from 4.10 to 5.72 after allowing 13 runs and 18 hits over his last two starts. The 30-year-old will make his next start Wednesday at home against the Yankees. He allowed three runs -- two earned -- over six innings in his previous meeting against the Yankees on April 13.