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NBA picks: Karl-Anthony Towns part of Cavaliers vs. Knicks same-game parlay for Game 2 on Thursday, May 21

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The New York Knicks emerged victorious in Game 1 of the Eastern Conference Finals over the Cleveland Cavaliers, who collapsed in the fourth quarter and overtime. The Cavs will need to bounce back in Game 2 on Thursday in order to even this series up, and it will be interesting to see how Cleveland guard James Harden recovers as he had yet another playoff game with more turnovers than field goals made in Game 1. Jalen Brunson again led the charge for New York with 38 points, and OG Anunoby returned to the lineup to deepen the Knicks' rotation. Tipoff at Madison Square Garden is scheduled for 8 p.m. ET and both teams have clean injury reports.

We've put together a same-game parlay for Cavaliers vs. Knicks Game 2 for those interested in parlay betting. We're using odds from FanDuel Sportsbook and recommendations from the SportsLine Projection Model, which simulates every game 10,000 times. The model entered the conference finals of the 2026 NBA playoffs on a sizzling 26-10 roll (72%) on top-rated NBA spread picks this season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Use the latest FanDuel promo code for a great offer when betting on Cavaliers vs. Knicks in the NBA Playoffs.

Cavaliers vs. Knicks Game 2 same-game parlay picks

Same-game parlay odds: +603

Knicks -5.5

Just how deflated will Cleveland be after blowing Game 1 in such dramatic fashion? Just how involved will Donovan Mitchell be with the offense after he barely touched the ball in overtime? Did Harden expend his last ounce of excellence in the Pistons series, or can he bounce back with a superstar performance for Game 2? Between Cleveland's issues and the magic of a Madison Square Garden crowd that believes the Knicks can go to the Finals, it's hard to go against New York on the spread. Look for Brunson and the Knicks to head to Cleveland with a 2-0 lead. New York covers in 63% of the model's simulations.

Karl-Anthony Towns Over 17.5 points

Towns was just 1-for-5 from downtown in Game 1, which helped contribute to a paltry 13-point showing for the big man. But the Knicks as a whole struggled with the longball, and we should expect some regression to the mean in Game 2. The Cavs also showed some willingness to hack Mitchell Robinson even with an early lead in the third quarter, which could prompt Mike Brown to keep Towns on the floor longer. Look for Towns to get some better shots while also using his size to his advantage inside. The SportsLine props model has a 20.5-point projection for Towns.

Mikal Bridges Over 19.5 points + rebounds + assists

Bridges was excellent in Game 1, finishing with 18 points, five rebounds and an assist (along with two steals). This is the version of Bridges the Knicks originally traded for -- a do-it-all pest. Even if Bridges takes a step back in the scoring department, he's still good enough in other facets of his game to clear this line. The SportsLine model projects Bridges at 23.1 PRA.

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