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Teams looking to get back on track clash when the Houston Rockets take on the Oklahoma City Thunder in a key Western Conference matchup on Saturday. Houston is coming off a 109-99 loss to Charlotte on Thursday, while Oklahoma City dropped a 116-106 decision at San Antonio on Wednesday. The Rockets (31-19), who are second in the Southwest Division, are 14-13 on the road this season. The Thunder (40-12), who are the top seed in the West and first in the Northwest Division, are 22-4 on their home floor. Shai Gilgeous-Alexander (abdominal strain) and Jalen Williams (hamstring) are out for OKC. 

Tipoff from Paycom Center in Oklahoma City is set for 3:30 p.m. ET. The Thunder lead the all-time series 126-119, including wins in each of the two meetings this season. Oklahoma City is a 2.5-point favorite in the latest Rockets vs. Thunder odds from DraftKings Sportsbook, while the over/under for total points scored is 211.5. Before making any Thunder vs. Rockets picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 16 of the 2025-26 NBA season on a sizzling 38-16 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.   

Now, the model has simulated Rockets vs. Thunder 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Thunder vs. Rockets:

Rockets vs. Thunder spread:    

Oklahoma City -2.5 at DraftKings    

Rockets vs. Thunder over/under:    

211.5 points

Rockets vs. Thunder money line:    

Oklahoma City -142, Houston +119

Rockets vs. Thunder picks:    

See picks at SportsLine

Rockets vs. Thunder streaming:

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How to make Rockets vs. Thunder picks

After 10,000 simulations of Rockets vs. Thunder, SportsLine's model is going Over on the total (211.5). The Over has hit in seven of the last 10 head-to-head meetings. The Over has also hit in seven of the last 10 Oklahoma City games. 

The SportsLine model is projecting Houston's Kevin Durant to score 22.8 points on average and be one of six Rockets players to score 10.6 or more points. Oklahoma City's Chet Holmgren is one of six players for OKC to score in double figures as he leads the way with 19.5 projected points. The model is projecting 221 combined points as the Over clears 62% of the time.

It has also generated an against-the-spread pick that hits in nearly 60% of simulations. You can head to SportsLine to see the model's NBA picks

So who wins Thunder vs. Rockets, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the Rockets vs. Thunder spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.