Spurs vs. Rockets odds, prediction, time: 2026 NBA picks for Tuesday, January 20 from proven model

The top two teams in the Southwest Division clash when the San Antonio Spurs battle the Houston Rockets in a key Western Conference matchup on Tuesday. San Antonio is coming off a 123-110 win over the Utah Jazz on Monday, while Houston defeated the New Orleans Pelicans 119-110 on Sunday. The Spurs (30-13), who are 7-1 within the division, are 13-8 on the road this season. The Rockets (25-15), who are 3-4 against the Southwest Division, are 14-3 on their home court. Houston will be without center Steven Adams (ankle).

Tipoff from Toyota Center in Houston is set for 8 p.m. ET. Houston is a 4.5-point favorite in the latest Spurs vs. Rockets odds from DraftKings Sportsbook, while the over/under for total points scored is 220.5. Before making any Rockets vs. Spurs picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 14 of the 2025-26 NBA season on a sizzling 35-15 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.   

Now, the model has simulated Spurs vs. Rockets 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Rockets vs. Spurs:

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How to make Spurs vs. Rockets picks

SportsLine's model is going Over on the total (220.5 points). The total has gone Over in two of the last three head-to-head meetings between the Spurs and Rockets. San Antonio is 4-3 against the spread in its last seven games, while Houston is 2-8 ATS in its last 10. The SportsLine model is projecting San Antonio's Victor Wembanyama to score 20.5 points on average and be one of five Spurs players to score 10 or more points. Houston's Kevin Durant, meanwhile, is projected to have 24.6 points as six Rockets players score 11 points or more as the Over hits 53% of the time.

It has also generated an against-the-spread pick that hits in nearly 70% of simulations. You can head to SportsLine to see the model's NBA picks. 

So who wins Spurs vs. Rockets, and which side of the spread hits nearly 70% of the time? Visit SportsLine now to see which side of the Spurs vs. Rockets spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.