The Colts could be without a number of key contributors on the defensive side of the ball in Week 3 against the 49ers, based on Friday's injury report. Safety LaRon Landry has already been ruled out, while Antoine Bethea is officially questionable with a toe injury. Defensive lineman Cory Redding is questionable with a back injury, while linebacker Pat Angerer is doubtful due to a knee injury.  Kavell Conner (ankle) is the only defensive player considered probable.