Skip to Main Content

Lions vs. 49ers Live updates Score, results, highlights, for Sunday's NFL game

The San Francisco 49ers and the Detroit Lions will face off at 1 p.m. ET Sept. 12 at Ford Field to kick off their 2021 seasons. San Francisco struggled last year, ending up 6-10. Likewise, last year was nothing to brag about for Detroit (5-11), either, so the team is looking forward to a new start.

A couple defensive numbers to keep in mind before kickoff: The 49ers were fourth best in rushing touchdowns allowed, finishing the 2020 season giving up only 12. Less enviably, Detroit ranked worst with respect to touchdowns allowed last season, where the squad gave up 65. The good news for Detroit, of course, is that these forces working against them might not carry over into the new season.

San Francisco has the odds in their favor, so they'll need to guard against complacency. A victory is hardly a sure thing, especially this early in the season, so expect a good game.

Updates
(96)
See New Posts
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:55 PM
Sep. 12, 2021, 4:55 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:51 PM
Sep. 12, 2021, 4:51 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:42 PM
Sep. 12, 2021, 4:42 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:41 PM
Sep. 12, 2021, 4:41 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 8:27 PM
Sep. 12, 2021, 4:27 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:26 PM
Sep. 12, 2021, 4:26 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:20 PM
Sep. 12, 2021, 4:20 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:17 PM
Sep. 12, 2021, 4:17 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:14 PM
Sep. 12, 2021, 4:14 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:14 PM
Sep. 12, 2021, 4:14 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:09 PM
Sep. 12, 2021, 4:09 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:07 PM
Sep. 12, 2021, 4:07 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:07 PM
Sep. 12, 2021, 4:07 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 8:06 PM
Sep. 12, 2021, 4:06 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:54 PM
Sep. 12, 2021, 3:54 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:40 PM
Sep. 12, 2021, 3:40 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:31 PM
Sep. 12, 2021, 3:31 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:27 PM
Sep. 12, 2021, 3:27 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:27 PM
Sep. 12, 2021, 3:27 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:19 PM
Sep. 12, 2021, 3:19 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:19 PM
Sep. 12, 2021, 3:19 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 7:17 PM
Sep. 12, 2021, 3:17 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:11 PM
Sep. 12, 2021, 3:11 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 7:09 PM
Sep. 12, 2021, 3:09 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:54 PM
Sep. 12, 2021, 2:54 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:47 PM
Sep. 12, 2021, 2:47 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 6:46 PM
Sep. 12, 2021, 2:46 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:32 PM
Sep. 12, 2021, 2:32 pm EDT
 
Pinned
Link copied
@Lions via Twitter
September 12, 2021, 6:32 PM
Sep. 12, 2021, 2:32 pm EDT
 
Pinned
Link copied
@49ers via Twitter
September 12, 2021, 6:30 PM
Sep. 12, 2021, 2:30 pm EDT
See More
Now Playing
Share Video
Link copied!
  • Image thumbnail
    1:50

    Carson Wentz to Start for Vikings with Kyler Murray Out

  • Image thumbnail
    1:25

    Which Backup QB Can Lead Their Team to Win in Week 9?

  • Image thumbnail
    1:45

    Mindset of Playing With a Backup Quarterback

  • Image thumbnail
    1:57

    Do The Steelers Need Another WR?

  • Image thumbnail
    1:28

    Jaguars Approach Ahead of the Trade Deadline

  • Image thumbnail
    1:11

    Does Detroit Need to Bolster Their Defense?

  • Image thumbnail
    1:09

    Is Trevor Lawrence a Top 5 NFL Quarterback?

  • Image thumbnail
    1:30

    AFC Playoff Picture: Who Could Disrupt the Top 7?

  • Image thumbnail
    1:29

    Broncos Eye No. 1 Seed in AFC as Division Odds Surge

  • Image thumbnail
    1:31

    Are the Jaguars Bona Fide Super Bowl Contenders?

  • Image thumbnail
    1:27

    Top Trade Destinations for Khalil Mack: Chicago Bears

  • Image thumbnail
    1:18

    Top Trade Destinations for Khalil Mack: No. 3 49ers

  • Image thumbnail
    1:23

    Top Trade Destinations for Khalil Mack: No. 2 Bills

  • Image thumbnail
    1:04

    Ravens Outlook with Joe Fagnano

  • Image thumbnail
    1:24

    Drew Lock's Week 9 Outlook

  • Image thumbnail
    1:35

    NFL Week 9 Survivor Pick: Seattle Seahawks

  • Image thumbnail
    1:34

    Drew Lock to Start for Seahawks with Sam Darnold Out

  • Image thumbnail
    1:09

    Eagles Turn to Joe Milton III, Bench Tanner McKee

  • Image thumbnail
    1:47

    Reports: Ravens Finalizing Trade For Jacoby Brissett

  • Image thumbnail
    1:46

    What To Make of Ashton Jeanty and the Raiders RB Room