Seahawks quarterback Russell Wilson heads into a tough Week 2 matchup at home against the 49ers.

Wilson had mixed results against the 49ers last season, however, the last time Wilson faced the 49ers at home, he fired four touchdown passes and completed 15 of 21 attempts for 171 yards. He has totaled 293 yards passing with four touchdowns and two interceptions in two career games against San Francisco.

Wilson, who cracked the 300-yard mark in Week 1 at Carolina, should have a tough time moving the chains against San Francisco's defense, even through the 49ers allowed 333 yards and three passing touchdowns to Aaron Rodgers last week. At this point, there are other quarterbacks with better Fantasy matchups heading into Week 2. Consider Wilson a low-end starting option in deeper formats for Week 2.

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