The 2025 NFL Playoffs continue this week with the NFL Divisional Round and there are four games on this week's NFL schedule. In the NFC, we'll see Lions vs. Commanders on Saturday and Eagles vs. Rams on Sunday. In the AFC, it's Chiefs vs. Texans on Saturday, followed by Bills vs. Ravens on Sunday. The latest 2025 Divisional Round NFL odds list the Chiefs (-8.5) and Lions (-9.5) as NFL favorites on Saturday, while the Ravens (-1) and Eagles (-6) are favored on Sunday.
Who wins all four Divisional Round NFL games and how should you handle your NFL picks against the spread, NFL over-under picks, and NFL money line picks? Before you make any Divisional Round NFL picks and postseason NFL score predictions, you need to see the NFL against the spread, NFL over-under, and NFL money line predictions powered by the self-learning SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score.
Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit a whopping 1,390 4.5- and 5-star NFL prop picks since the start of last season at 48% accuracy. Unders of any grade hit at a 54.5% clip. It also nailed six of its seven A+ picks during NFL Wild Card Weekend 2025.
For divisional round NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting picks for all four games. You can only see the AI predictions for the 2025 NFL Divisional Round here.
Top NFL Divisional Round AI picks
After analyzing every game during NFL Divisional Round 2025, the AI PickBot says the Bills cover comfortably as one-point home underdogs against the Ravens on Sunday (O/U 51.5). The AFC East and AFC North champions met in Baltimore earlier this season and Lamar Jackson's squad cruised to a 35-10 victory. However, the rematch will take place in Buffalo and the Bills had the edge when these two teams last played a postseason game in Western New York.
Josh Allen led the squad to a 17-3 win as 2.5-point favorites in frigid conditions during the 2021 NFL Divisional Round and the MVP frontrunner is coming off another dominant win over the Broncos. Allen went 20-for-26 for 272 yards and two touchdowns while adding 46 yards on the ground in a 31-7 win as 8.5-point home favorites.
With snow showers in the forecast all week, the advantage likely goes to Buffalo with regards to conditions and Allen will have another chance at a legacy moment in a premier matchup with Jackson, a two-time NFL MVP. The AI PickBot rates a Bills cover as an A+ pick and also predicts a 32-22 win. See its other NFL Divisional Round score predictions and football picks at SportsLine.
How to make NFL Divisional Round predictions
The AI PickBot has generated a total of four highly-coveted A+ picks for NFL Divisional Round 2025, including another underdog to win outright for a big payout. You need to see the AI PickBot's NFL picks before making any NFL Divisional Round bets of your own. You can only see them at SportsLine.
Who wins and covers each NFL Divisional Round game, and which A+ picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the self-learning SportsLine AI PickBot that has nailed 1,390 top-rated picks since the start of last season and nailed six of seven top-rated Wild Card picks.
