The initial College Football Playoff rankings were revealed Tuesday night and it was no surprise that Oregon was ranked No. 1. Oregon beat Michigan 38-17 last week, giving the Ducks a 9-0 record heading into their matchup against Maryland on Saturday during the Week 11 college football schedule. They are 23.5-point favorites, down from opening at -25.5, in the Week 11 college football odds via SportsLine consensus. No. 2 Ohio State is also a massive favorite in the Week 11 college football spreads, listed at -37.5 against Purdue. Should you back either of those heavy favorites to cover with your Week 11 college football bets? 

No. 3 Georgia finds itself in a much different situation, as the Bulldogs are just 1.5-point road favorites at No. 16 Ole Miss on Saturday afternoon. Later in the day, No. 15 LSU (+2.5) hosts No. 11 Alabama in a game that will likely eliminate the loser from the College Football Playoff picture. Before locking in any Week 11 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 18-9 on all top-rated picks over the past six weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

Now, it has turned its attention to the latest college football odds and Week 11 college football betting lines. Head here to see every pick.

No ad available

Top college football predictions for Week 11 

One of the college picks the model is high on during Week 11: Michigan (+14.5) easily stays within the spread at No. 8 Indiana in a 3:30 p.m. ET matchup on Saturday. The Hoosiers have won all nine of their games this season and have covered the spread in their last eight wins, but they have yet to face a team receiving a single vote in the AP poll. They will face one of their toughest challenges to date on Saturday, as Michigan's elite defense and rushing attack make them a difficult team to blow out. 

The Wolverines only trailed No. 1 Oregon by 11 points with one minute remaining in the third quarter before giving up a pair of late touchdowns, but senior quarterback Davis Warren had one of his best performances of the season. He completed 13 of 23 passes for 165 yards and two touchdowns, while senior running back Donovan Edwards averaged 5.2 yards per carry. Michigan has won 10 of its last 11 games at Indiana, and the model has the Wolverines covering the spread in more than 60% of simulations. See the rest of its Week 11 college football picks here. 

Another prediction: No. 6 Penn State (-12.5) cruises to a blowout win over Washington in an 8 p.m. ET kickoff on Saturday. The Nittany Lions are coming off their first loss of the season, once again failing to beat Ohio State late in the year. They cannot afford another loss as they try to stay on track for a College Football Playoff spot, so bettors can expect a focused effort from them on Saturday night, especially since this is the annual White Out game. 

No ad available

Junior quarterback Drew Allar should be healthier after dealing with a lingering injury against the Buckeyes last week, while running backs Kaytron Allen and Nicholas Singleton are one of the best duos in the country. Washington has suffered two double-digit losses in its last three games, including a 40-16 setback at Iowa last month. The Huskies do not have enough firepower to keep pace in this matchup, as the model has Penn State covering the spread 60% of the time. See picks for every other game in Week 11 here.

How to make college football picks for Week 11

The model has also made the call on who wins and covers in every FBS matchup in Week 11, and it's calling for six underdogs to win outright, including an upset in one of the biggest games of the week. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence, and which six underdogs win outright in Week 11? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception, and find out.

No ad available

College football odds for Week 11

See full Week 11 college football picks, odds, predictions here

Saturday, Nov. 9

Miami (FL) at Georgia Tech (+10, 63.5)

Florida at Texas (-21.5, 47.5)

Purdue at Ohio State (-37.5, 53)

Georgia at Ole Miss (+1.5, 54.5)

Michigan at Indiana (-14.5, 48.5)

Colorado at Texas Tech (+4.5, 62.5)

Maryland at Oregon (-23.5, 58.5)

Florida State at Notre Dame (-25, 42.5)

Alabama at LSU (+2.5, 60.5)

No ad available

Nevada at Boise State (-24, 60.5)

Washington at Penn State (-12.5, 46.5)

BYU at Utah (+3.5, 40.5)

No ad available