The Vanderbilt Commodores and the No. 7 Missouri Tigers are set to square off in an SEC battle at 4:15 p.m. ET on Saturday at Memorial Stadium/Faurot Field. Missouri is 3-0 overall and 3-0 at home, while Vanderbilt is 2-1 overall and 0-1 on the road. Both teams are 2-1 against the spread this season.
Missouri is favored by 20.5 points in the latest Missouri vs. Vanderbilt odds via SportsLine consensus, and the over/under is 53.5 points. Before entering any Vanderbilt vs. Missouri picks, you'll want to see the college football predictions from the model at SportsLine.
The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.
The model has set its sights on Vanderbilt vs. Missouri. You can head to SportsLine to see its picks. Here are several college football betting lines for the spread, money line and over/under for the game:
- Missouri vs. Vanderbilt spread: Missouri -20.5
- Missouri vs. Vanderbilt over/under: 53.5 points
- Missouri vs. Vanderbilt money line: Missouri -1408, Vanderbilt +806
- Missouri vs. Vanderbilt picks: See picks here
What you need to know about Vanderbilt
After a surprising start to the season that included an upset of Virginia Tech and a 55-0 blowout of Alcorn State, Vanderbilt had a setback in Week 3, losing 36-32 at Georgia State. The Commodores still saw big numbers from quarterback Diego Pavia, who threw for 270 yards and two touchdowns. Another player making a difference was Eli Stowers, who picked up 110 receiving yards and a touchdown.
Pavia, a transfer from New Mexico State, has given this offense some life after the Commodores struggled to find consistency at the position last year. For the season, he's 40-of-62 passing for 543 yards, four touchdowns and no interceptions. He's added 195 yards and two scores on the ground. See who to back at SportsLine.
What you need to know about Missouri
Meanwhile, Missouri got another win last Saturday to keep its perfect season alive. The Tigers snuck past Boston College with a 27-21 victory. The Tigers had no problem finishing drives, scoring a touchdown on all four of their trips to the red zone.
Brady Cook was the offensive standout of the contest as he threw for 264 yards and a touchdown, and also punched in a touchdown on the ground. Nate Noel had a big day on the ground, rushing for 121 yards. Receiver Luther Burden III is also a big part of this offense as the likely first-round pick in the 2025 NFL Draft has 13 receptions for 181 yards and two touchdowns thus far. See who to back at SportsLine.
How to make Missouri vs. Vanderbilt picks
The model has simulated Missouri vs. Vanderbilt 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits more than 50% of the time. You can only see the pick at SportsLine.
Who wins Vanderbilt vs. Missouri, and which side of the spread hits more than 50% of the time? Visit SportsLine now to find out, all from the model that's returned more than $2,000 on its top-ranked college football spread picks since inception.
