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The No. 7 Tennessee Volunteers (6-1) will continue their four-game homestand when they host the Kentucky Wildcats (3-5) on Saturday night. Tennessee opened the homestand with wins over Florida and then-No. 7 Alabama before having a bye last week. Kentucky is on a three-game losing skid following a 24-10 loss to Auburn, putting its postseason hopes in jeopardy. Tennessee has won 13 of the last 14 meetings between these teams in Knoxville. 

Kickoff is set for 7:45 p.m. ET on Saturday at Neyland Stadium. Tennessee is favored by 17.5 points in the latest Tennessee vs. Kentucky odds, while the over/under is 45.5 points, per SportsLine consensus. Before entering any Kentucky vs. Tennessee picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

The model has set its sights on Kentucky vs. Tennessee. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:

  • Tennessee vs. Kentucky spread: Tennessee -17.5
  • Tennessee vs. Kentucky over/under: 45.5 points
  • Tennessee vs. Kentucky money line: Tennessee -1000, Kentucky +628
  • Tennessee vs. Kentucky picks: See picks here
  • Tennessee vs. Kentucky streaming: FuboTV (Try for free)

Why Tennessee can cover

Tennessee lost to Arkansas as a 14-point road favorite at the beginning of October, but it has responded with rivalry wins over Florida and Alabama. The Vols were 3.5-point home underdogs in their win over the Crimson Tide two weeks ago, as running back Dylan Sampson had 139 rushing yards and two touchdowns. Sampson has been one of the top players at his position in college football, racking up 840 yards and 17 touchdowns. 

Sampson has gone over 90 rushing yards in every game this season, taking some pressure off redshirt freshman quarterback Nico Iamaleava. The Vols also have a defense that ranks third nationally in points allowed per game (11.6) and total defense (259 yards per game). They have won 36 of the last 39 meetings between these teams, including a 38-point win at home two years ago. See which team to pick here.

Why Kentucky can cover

Kentucky is desperately looking to turn its season around following its recent three-game losing streak. The Wildcats have proven they can compete with the best teams in the SEC, nearly upsetting then-No. 1 Georgia in September before pulling off a big upset against then-No. 6 Ole Miss. They were 17.5-point underdogs in that game, but junior quarterback Brock Vandagriff had 243 passing yards and a touchdown. 

Vandagriff did not thrown an interception against Georgia or Ole Miss, and a clean performance on Saturday will help keep Kentucky in the game. Tennessee's win over Alabama came after an overtime win against Florida and an outright loss to Arkansas, so the Vols have not been winning games with this type of margin since early in the season. They have only covered the spread five times in their last 15 games in November, while Kentucky has covered in eight of its last 12 road games. See which team to pick here.

How to make Tennessee vs. Kentucky picks

The model has simulated Kentucky vs. Tennessee 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 50% of the time. You can only see the pick at SportsLine.

So who wins Tennessee vs. Kentucky, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Kentucky vs. Tennessee spread to jump on, all from the advanced computer model that's up well over $2,000 on its top-rated college football spread picks since its inception, and find out.