The Red Sox activated Yoshida (shoulder) from the 60-day injured list Wednesday.
Yoshida is finally ready to make his season debut for the Red Sox after a long recovery from offseason surgery on his right shoulder. The 31-year-old will start at designated hitter and will bat sixth in Wednesday's game versus righty Antonio Senzatela and the Rockies. Yoshida might have to get off to a good start if he wants to see regular playing time, as the Red Sox have lots of mouths to feed between the outfield and DH.