The Guardians selected Peterson's contract from Triple-A Columbus on Tuesday, Zack Meisel of The Athletic reports.

Peterson struggled a bit after being promoted to Triple-A in June, posting a 4.27 ERA and 1.37 WHIP across 90.2 innings compared to the 1.47 ERA and 0.82 WHIP he held in 55 frames at Double-A Akron. The 26-year-old's addition to the 40-man roster will prevent him from being selected in the Rule 5 Draft, but the Guardians will likely keep him in Triple-A to begin the 2026 campaign.

Colorado traded Ward to Boston on Tuesday in exchange for left-handed reliever Brennan Bernardino, Patrick Saunders of The Denver Post reports.

Ward is a 26-year-old speedster who stole 57 bases in 64 attempts across Double-A and Triple-A last season. He also batted a healthy .290 over 97 games, but he has very little power, as he went deep just twice in the minors in 2025. Ward has played all three outfield positions as well as second base and third base in the minors, so if he makes it to the majors, he best profiles as a utility player and speed specialist.

The Orioles designated Vazquez for assignment Tuesday.

Vazquez re-signed with Baltimore on a one-year contract in late October but will end up having a short stay on the 40-man roster. The 26-year-old appeared in 36 games for the O's last season and had a .160/.208/.240 slash line in 53 plate appearances.

Enright (elbow) was designated for assignment by the Guardians on Tuesday, Zack Meisel of The Athletic reports.

Enright loses his 40-man spot on Rule 5 deadline day after undergoing Tommy John surgery shortly after the end of the 2025 regular season. He will miss all of 2026, but Enright showed real promise before going down with a 2.03 ERA and 1.16 WHIP over 31 innings out of the Cleveland bullpen, numbers which may attract a team on the other end of the competitive spectrum.

The Orioles designated Leon (knee) for assignment Tuesday.

The 27-year-old was claimed off waivers by Baltimore earlier in November but is already off the 40-man roster. Leon spent the 2025 season on the injured list due to knee issues, though he did play in 25 rehab games in the minors.

Rainey was designated for assignment by the Tigers on Tuesday, Cody Stavenhagen of The Athletic reports.

Rainey's relevance in the fantasy world was fleeting, as he quickly fell off the map after the 2020 season. He has bounced from Washington to Pittsburgh to Detroit in recent years while mostly struggling on the mound. He pitched to an ugly 11.17 ERA and 1.76 WHIP over 9.2 major-league innings in 2025.

The Orioles selected Foster's contract from Triple-A Norfolk on Tuesday.

The 26-year-old was acquired from the Mets in the Gregory Soto trade over the summer, so his addition to the 40-man roster was to be expected. Foster pitched in 13 games for Triple-A Norfolk after the trade and had a 3.38 ERA, 1.38 WHIP and 23:8 K:BB over 16 innings.

The Tigers designated Mattison for assignment Tuesday, Cody Stavenhagen of The Athletic reports.

Mattison was added to the 40-man roster last November, but he finds himself on the other side of Rule 5 cutdown day this time around. The right-hander has yet to make his major-league debut. He pitched mostly between Double-A and Triple-A this past season after recovering from right UCL reconstruction surgery.

Little was designated for assignment by the Tigers on Tuesday, Cody Stavenhagen of The Athletic reports.

Claimed off waivers from the Pirates earlier this month, Little ended up spending less than two weeks on the Tigers' 40-man roster. Little will now be subjected to waivers once again after spending the 2025 season primarily at the Triple-A level, making just a pair of relief appearances with the Dodgers over the summer.

Guenther (hip) was designated for assignment by the Tigers on Tuesday, Cody Stavenhagen of The Athletic reports.

Left hip surgery ended Guenther's season in early July after he made nine appearances (one start) with the big-league club over the first two months of the campaign. The left-hander put an impressive 0.86 ERA and 0.52 WHIP in 21 innings out of the Detroit bullpen during the 2024 regular season, and that run of success may be enough to land him on another team's 40-man roster.