The Texans have the best tight end duo in the NFL right now with Owen Daniels and Garrett Graham, and both rank in the Top 12 of standard Fantasy leagues. But this should be a tough week for them at San Francisco, and you might want to keep them reserved if possible.
The 49ers gave up a touchdown to Jermichael Finley in Week 1, but since then San Francisco has been stout against tight ends. Lance Kendricks scored a late touchdown in Week 4, but Coby Fleener and Jared Cook have combined for six catches for 58 yards the previous two games.
Daniels played well in Week 4 against Seattle with six catches for 72 yards, but he's now gone two games in a row without a touchdown. After scoring 18 Fantasy points in the first week of the season, he has combined for 17 points the past three games.
Graham has scored in three of four games this year, but he's only averaging four targets a week, which makes him a risky play. If he doesn't score a touchdown you're looking at a high of about three Fantasy points.
Based on the tough matchup, we would only consider starting Daniels in deeper leagues and leaving Graham in a reserved role.