Bredeson (concussion) has been ruled out for the Giants' Week 3 matchup with the 49ers on Thursday Night Football, Dan Salomone of the Giants' official site reports.
Bredeson suffered a concussion in Sunday's 31-28 win over the Cardinals, and he will now officially be forced to sit out at least one contest while recovering. Shane Lemieux will likely take over at left guard in Week 3.