The Saints placed Ingram (knee) on injured reserve Wednesday, Field Yates of ESPN reports.
Ingram suffered an MCL tear in a Week 13 loss to Tampa Bay, likely leaving him with a recovery and rehab timeline of 4-to-6 weeks. He's now officially ruled out for the remainder of the regular season, and he might not be ready for the start of the playoffs even in the highly unlikely scenario that the Saints earn a spot. New Orleans is left with Eno Benjamin, David Johnson and Dwayne Washington as its depth options behind top running back Alvin Kamara.