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Matt Barkley QB | JAC
Bills' Matt Barkley: Takes over for concussed Allen
Barkley came in for the injured Josh Allen (concussion) and completed nine of 16 passes for 127 yards and an interception in Sunday's 16-10 loss to the Patriots.
Barkley was called into action after Josh Allen took a vicious helmet-to-helmet hit early in the fourth quarter. He immediately led the team down to the 2-yard line before turning it over on downs. That's as close as the Bills would come to erasing a six-point deficit, as a Barkley interception in New England territory with 1:27 to play sealed their fate. Allen went to the locker room under his own power but couldn't clear the concussion protocol. Barkley would start in Week 5 against the Titans if Allen is unable to clear the protocol by then.
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Mitch Trubisky QB | TEN
Bears' Mitchell Trubisky: Has shoulder injury, ruled out
Trubisky suffered a left shoulder injury during Sunday's game against the Vikings and won't return.
Trubisky got injured on a play that ultimately didn't count, as it was nullified by a defensive penalty on the Vikings. The Bears have yet to release the precise injury, but Trubisky will yield QB duties to backup Chase Daniel for the rest of the afternoon.
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Deshaun Watson QB | CLE
Texans' Deshaun Watson: Scores rushing touchdown
Watson completed 21 of 33 pass attempts for 160 yards with no touchdowns or interceptions Sunday against the Panthers. He also carried three times for 12 yards and a touchdown in the 16-10 loss.
Watson generated little in the way of big plays, finishing with an average of 4.8 yards per attempt while failing to exceed 160 passing yards for the second time this season. He did get into the end zone on a one-yard touchdown run in the third quarter, giving him three rushing scores in four games, but it was still a disappointing performance overall. Although Watson has been quite inconsistent this season, next Sunday's home matchup against the Falcons should present him with a bounce-back opportunity.
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Patrick Mahomes QB | KC
Chiefs' Patrick Mahomes: Breaks Detroit's heart
Mahomes completed 24 of 42 passes for 315 yards and added 54 yards on six rushes during Sunday's 34-30 win over the Lions.
The Lions were a play away from capping off the upset in the final moments of Sunday's game when, facing 4th-and-8, Mahomes drifted back, found a lane, and scooted upfield for a gain of 15, setting up the game-winning touchdown. Playing a Detroit defense that has frustrated a Pro Bowl's worth of quarterbacks already this season, Mahomes wasn't playing pitch and catch as he typically does and was held without a touchdown for the first time since Week 5 of last season. Sunday showed that Mahomes is mortal; it just so happens that mortal -- for him -- still includes 369 total yards.
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Lamar Jackson QB | BAL
Ravens' Lamar Jackson: Ugly but effective in loss
Jackson completed 24 of 34 passes for 247 yards, three touchdowns and two interceptions in Sunday's 40-25 loss to Cleveland. He added 66 yards on nine carries.
Jackson threw for only 34 yards in the first half, but that total included a nine-yard touchdown pass to Miles Boykin just after the two-minute warning. He added an eight-yard touchdown to Mark Andrews in the fourth quarter but got picked off twice after that to dim Baltimore's comeback hopes before connecting for a 50-yard score with Willie Snead in garbage time. While Jackson has made strides as a passer, he's still much more comfortable operating with a run-pass balance, though big deficits open up the possibility of fantasy-friendly garbage-time production. Jackson remains a high-tier fantasy quarterback ahead of a Week 5 trip to Pittsburgh.
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Josh Allen QB | BUF
Bills' Josh Allen: Officially in concussion protocol
Allen is in the concussion protocol after suffering a hit during Sunday's 16-10 loss to the Patriots, Joe Buscaglia of The Athletic reports.
Allen suffered a helmet-to-helmet hit during Sunday's divisional contest and did not return to the game. He was replaced by Matt Barkley under center. The second-year quarterback will need to fully clear the league's five-step protocol for head injuries before reentering the starting lineup.
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Mitch Trubisky QB | TEN
Bears' Mitchell Trubisky: Under evaluation for injury
Trubisky went to the locker room during the first quarter of Sunday's contest versus the Vikings, Arif Hasan of The Athletic reports.
Trubisky got flushed to his left and coughed up the ball to the Vikings at the end of the play, but the turnover was nullified by a defensive penalty. The nature of his injury hasn't been released, but the Bears sent in Chase Daniel to replace Trubisky.
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Marcus Mariota QB | WAS
Titans' Marcus Mariota: Three-touchdown performance
Mariota completed 18 of 27 pass attempts for 227 yards and three touchdowns in Week 4 against Atlanta. He also added three rushes for 22 yards.
Mariota jumped out to a hot start, completing 14 of his 19 first-half pass attempts, accounting for all three of his touchdowns and 189 yards. He formed a particular connection with rookie wideout A.J. Brown, delivering touchdowns of 55 and 11 yards to him. With the Titans in command of the game throughout the second half, the team focused on running the ball, slowing Mariota's big performance. Still, his effort -- and the team's victory -- should keep him under center for the foreseeable future and ahead of Ryan Tannehill on the depth chart. Mariota will look to build on the performance in Week 5 against Buffalo.
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Baker Mayfield QB | TB
Browns' Baker Mayfield: Takes back seat to running game
Mayfield completed 20 of 30 passes for 342 yards, a touchdown and an interception in Sunday's 40-25 win over Baltimore. He added one rushing yard on three carries.
Mayfield hit Ricky Seals-Jones for a nine-yard touchdown in the first quarter as part of a first half in which he threw for 208 yards but led the team to only 10 points. Cleveland's offense shifted to a more run-heavy approach in the second half, with Nick Chubb rumbling for three touchdowns and Dontrell Hilliard adding another. Mayfield did most of his damage targeting Jarvis Landry -- who left the game with a concussion after catching eight balls for 167 yards -- but look for him to shift his focus back to Odell Beckham against the 49ers in Week 5 after the pair connected on only two of seven targets for 20 yards in this one.
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Kyle Allen QB | BUF
Panthers' Kyle Allen: Survives three fumbles
Allen completed 24 of 34 passes for 232 yards with no touchdowns or interceptions in the Panthers' 16-10 win over the Texans on Sunday. He also lost three fumbles.
Christian McCaffrey accounted for the Panthers' only touchdown with a three-yard rush shortly before halftime, yet Allen did enough through the air to keep the Texans honest and overcome his three fumbles. The second-year quarterback took three sacks and officially was hit five times overall, but he hung tough and ultimately helped lead two shorter fourth-quarter scoring drives, the second aided by a short field after a turnover. Allen connected with six different pass catchers on the afternoon, and he relied an inordinate amount on McCaffrey, who proved an excellent outlet option on 10 occasions. Allen has plenty to clean up in terms of ball security, but he should continue under center in a Week 5 home tilt against the Jaguars with Cam Newton (foot) expected to miss that contest.