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Latavius Murray RB | BUF
Bills' Latavius Murray: Works ahead of Harris
Murray carried the ball six times for 22 yards and one touchdown in Sunday's 38-10 win over the Raiders. He added two receptions on two targets for nine yards.
James Cook served as the lead back for the Bills, but Murray mixed in as early as the second possession. He capped that drive with a four-yard touchdown plunge and was also regularly on the field when the ball was inside the opponent's 10-yard line. That role will leave him as a touchdown-or-bust option, but it appears that he has jumped Damien Harris on the depth chart.
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De'Von Achane RB | MIA
Dolphins' De'Von Achane: Quiet pro debut
Achane (shoulder) had one carry for five yards and caught his lone target for four yards in Sunday's 24-17 win over the Patriots.
Achane was able to make his NFL debut after missing the Dolphins' first game due to a shoulder injury sustained in the preseason. The third-round rookie was used sparingly as starter Raheem Mostert carried the offense with 121 rushing yards and two scores. Fellow backup Salvon Ahmed suffered a groin injury in Sunday's win, so Achane may see his role increase against the Broncos next Sunday.
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Antonio Gibson RB | NE
Commanders' Antonio Gibson: Stuck in small role
Gibson had two carries for nine yards while catching all three of his targets for 44 yards in Sunday's 35-33 win over Denver.
Gibson was limited to just five touches a week after receiving four, giving way to starter Brian Robinson, who had a two-touchdown day. The veteran backup was able to break off a 36-yard reception out of the backfield but was otherwise a non-factor. Gibson has provided fantasy value in the past while serving as Washington's starter, but he is an unappealing option against Buffalo next Sunday in his current role.
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Matt Breida RB | SF
Giants' Matt Breida: Quiet Sunday but could start Week 3
Breida rushed once for five yards and wasn't targeted in the passing game Sunday in a win against Arizona in Week 2. However, top running back Saquon Barkley injured his ankle late in the contest, making Breida a candidate to start for New York this Thursday in San Francisco.
Breida's lone rush attempt Sunday came on the play after Barkley was injured with just over a minute left in the fourth quarter. Breida logged only three touches in a season-opening loss to Dallas, emphasizing the minimal role he has on offense when Barkley is healthy. However, with the Giants' star RB slated for an MRI on his ankle Monday, per Adam Schefter of ESPN, the door appears to be open for Breida to move in as the team's starter Thursday in San Francisco and possibly for additional time beyond that. The matchup against the 49ers is far from ideal, and there is hope among the organization that Barkley avoided a high-ankle sprain, so fantasy managers have a lot to consider when weighing how much to invest in grabbing Breida off the waiver wire.
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Raheem Mostert RB | LV
Dolphins' Raheem Mostert: Carries offense with two TDs
Mostert (knee) carried the ball 18 times for 121 yards and two touchdowns while catching his lone target for six yards in Sunday's 24-17 win over the Patriots.
Mostert was already on his way to a strong performance before ripping off a 41-yard touchdown run in the fourth quarter to put the Dolphins up for good. The veteran back was not limited by the minor knee injury he was dealing with during the practice week, commanding 18 carries with no other Miami back seeing more than three. Mostert has certainly outperformed his ADP so far, and he will look to keep things rolling against the Broncos next Sunday.
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Rhamondre Stevenson RB | NE
Patriots' Rhamondre Stevenson: Finds end zone in loss
Stevenson rushed 15 times for 50 yards and a touchdown while catching all three of his targets for 10 yards in Sunday's 24-17 loss to Miami.
Stevenson was heading for another down game before a late touchdown saved his fantasy day. The 25-year-old finished ahead of veteran Ezekiel Elliott (5-13-0) in carries for the second consecutive week, confirming his status as the lead back in New England. Stevenson has just 75 rushing yards through two games, but his ground production should increase when the Patriots' brutal early season schedule softens up. There is nothing soft about the Jets' defense, which will host Stevenson and the Patriots next Sunday.
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Damien Harris RB | BUF
Bills' Damien Harris: Gets garbage-time score
Harris carried the ball seven times for 33 yards and a touchdown in Sunday's 38-10 win over the Raiders.
On the surface, it appears that Harris saw a significant uptick in involvement in the Bills offense after a one-carry performance in Week 1. However, through three quarters, he had only two carries while Latavius Murray had already tallied all eight of his touches for the day. Given that, it appears that Harris has slipped to third on the depth chart, and he could be in danger of rarely taking the field in more competitive games.
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Dare Ogunbowale RB | LV
Texans' Dare Ogunbowale: Sees action in Week 2
Ogunbowale had two carries for four yards in Sunday's 31-20 loss to Indianapolis in Week 2.
Ogunbowale made his season debut after being inactive Week 1. He took the active spot that Mike Boone had last week and operated as the third back behind Dameon Pierce and Devin Singletary. One of Ogunbowale's carries came in the red zone.
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Devin Singletary RB | NYG
Texans' Devin Singletary: Quiet in loss
Singletary carried four times for 14 yards and caught his lone target for 10 yards in Sunday's 31-20 loss to the Colts in Week 2.
Singletary's 24 combined yards was an improvement over Week 1 (15 yards), and the target was his first of the season. The Texans ground game felt the negative impact of injuries across the offensive line. For a second straight week, the rushing attack was bottled up, and Houston's offense threw nearly twice as much as it ran. Unfortunately for the backs, all that passing hasn't resulted in many targets. Of 91 pass attempts through the first two games, the position group accounts for 11 targets. Early on, quarterback C.J. Stroud has heavily favored wideouts, which account for 60 targets.
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Saquon Barkley RB | PHI
Giants' Saquon Barkley: Likely avoided high-ankle sprain
The Giants are optimistic that Barkley (ankle) avoided a high-ankle sprain Sunday against the Cardinals and is dealing with a less severe regular sprain, but he will have an MRI on his ankle Monday to confirm that diagnosis, Jordan Raanan of ESPN.com reports.
Barkley was injured in the fourth quarter of Sunday's 31-28 win over Arizona. He was instrumental in the Giants' comeback from a 21-point deficit, scoring a rushing touchdown and a receiving touchdown. Even a regular ankle sprain would likely keep Barkley out of Thursday's game against the 49ers, but he would be projected to miss only one or two additional games if Monday's MRI confirms a regular sprain, while a high-ankle sprain usually entails a recovery of 4-to-6 weeks.