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James Robinson RB | NO
Jaguars' James Robinson: Big game on the ground
Robinson ran for 149 yards and one touchdown on 18 carries against Tennessee on Sunday.
Robinson couldn't draw any usage as a pass catcher as his one target resulted in a catch for minus-two yards. Although that makes two games in a row with minus-two receiving yards, Robinson again demonstrated his standout ability with the football by running through the Tennessee defense with ease. While his final line was mostly propelled by a 58-yard carry in the first quarter, his 91 yards on the other 17 carries illustrates his consistency aside from that big play. The Jaguars remain winless, but Robinson is their most effective player on offense and in recent weeks he's steadily built up momentum, scoring in three straight. The Dolphins have struggled to stop the run this year, and they face Robinson in Week 6.
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Najee Harris RB | NYG
Steelers' Najee Harris: Posts 122 rushing yards before exit
Harris carried 23 times for 122 yards and a TD in Sunday's 27-19 win over the Broncos, but he was forced out of the game in the fourth quarter with cramps and did not return, Joe Rutter of the Pittsburgh Tribune-Review reports.
Assuming no issues other than cramping are in play, Harris' Week 6 availability shouldn't be in any danger, though we'll track his status once the Steelers begin their prep for next Sunday's game against the Seahawks. Next up for the team's RB reps if Harris' practice reps end up impacted at all are Benny Snell and Kalen Ballage.
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Derrick Henry RB | BAL
Titans' Derrick Henry: Three-touchdown effort
Henry ran for 130 yards and three touchdowns on 29 carries against Jacksonville on Sunday.
Henry didn't get any chances as a pass catcher due to Tennessee throwing just 21 targeted passes, but his fantasy investors will always accept that tradeoff if it comes with 31 fantasy points on the ground alone. This game marks the fourth in row in which Henry breezed past triple-digit yardage on the ground, and there's a chance he gets more pass-catching opportunities when the Titans take on the Bills in Week 6.
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Damien Harris RB | BUF
Patriots' Damien Harris: Exits Sunday's game again
Harris was forced out of Sunday's game against the Texans with a rib injury.
Harris previously left the contest with a chest injury but was able to return. Now he's added a rib issue to his Week 5 injury woes and will need to be monitored in advance of next weekend's game against the Cowboys . While he's unavailable, Rhamondre Stevenson and Brandon Bolden are on hand to handle the team's backfield duties. Prior to his second exit from the game, Harris had carried 14 times for 58 yards and a TD.
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Damien Harris RB | BUF
Patriots' Damien Harris: Returns to action
Harris (chest) returned to Sunday's game against the Texans, Mike Reiss of ESPN.com reports.
Good news for the Patriots, who were down to Rhamondre Stevenson and Brandon Bolden at RB after Harris exited the contest. While Harris was out of the game, it was Stevenson -- in his first game since Week 1 -- who filled in as the team's top early-down back.
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Eno Benjamin RB | NO
Cardinals' Eno Benjamin: Active for first time
Benjamin (hamstring) is listed as active Sunday versus the 49ers.
For the first time in his career, Benjamin is active for an NFL game after the Cardinals made him a seventh-round pick in the 2020 draft. He may just be an emergency option, though, after lead running back Chase Edmonds dealt with a hamstring injury of his own during Week 5 prep. If the status quo holds, Edmonds and James Conner will be the primary RBs for Arizona, while Jonathan Ward serves on special teams and Benjamin waits for his first snap as a pro.
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Damien Harris RB | BUF
Patriots' Damien Harris: Picks up chest injury
Harris is questionable to return to Sunday's game against the Texans.
Harris had 10 carries for 27 yards and a touchdown before going down with the injury. He nearly scored a second touchdown but lost a fumble at the one-yard line. Rhamondre Stevenson has taken over as New England's primary tailback in his absence.
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Ezekiel Elliott RB | LAC
Cowboys' Ezekiel Elliott: Suits up Sunday
Elliott (knee) is listed as active for Sunday's game against the Giants, Jon Machota of The Athletic reports.
Elliott logged limited practices Thursday and Friday and was officially listed as questionable by the Cowboys, but he's in uniform Sunday and in line to continue to pace the team's ground game, while Tony Pollard works in a complementary role. In Dallas' Week 4 win over Carolina, Elliot recorded a season-high 20 rushing attempts for 143 yards and a TD.
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Chase Edmonds RB | WAS
Cardinals' Chase Edmonds: Suiting up Week 5
Edmonds (hamstring) is listed as active Sunday against the 49ers.
Edmonds didn't get on the practice field until Friday, when his reps were limited. At the time, coach Kliff Kingsbury called Edmonds a game-time decision, but the fourth-year running back seemingly has progressed enough to play through his shoulder injury. With Edmonds in the lineup Week 5, the Cardinals likely will utilize the same 1A and 1B backfield situation (Edmonds and James Conner) as the first four games of the campaign.
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Joshua Kelley RB | TEN
Chargers' Joshua Kelley: Active against Cleveland
Kelley is active for Sunday's game against Cleveland, Gilbert Manzano of The Orange County Register reports.
Kelley will be active for the first time this season, but he's not expected to have a large role in a backfield that's crowded and led by Austin Ekeler and Larry Rountree.