Hampton (ankle) has been ruled out for Sunday's regular-season finale against the Broncos.

Meanwhile, fellow RBs Kimani Vidal (neck) and Hassan Haskins (concussion) are both listed as questionable for Sunday's 4:25 p.m. ET kickoff, which presumably means that Jaret Patterson and/or Amar Johnson will be elevated from the Chargers' practice squad ahead of Week 18 action. Hampton's next chance to see game action thus is slated to arrive in the team's playoff opener during the wild-card round.

Haskins (concussion) is officially listed as questionable for Sunday's regular-season finale against the Broncos.

Haskins will need to gain full clearance from the NFL's concussion protocol, including from an independent neurologist, in order to be eligible to suit up Sunday versus Denver. Meanwhile, Omarion Hampton (ankle) has been ruled out for Week 18 while Kimani Vidal (neck) is listed as questionable. Head coach Jim Harbaugh has already stated that the Chargers will rest some starters in preparation for the team's looming playoff run, so if he's cleared to play, Haskins could be in line for an elevated role on offense.

Achane (shoulder) is officially listed as doubtful for Sunday's season finale against the Patriots, David Furones of the South Florida Sun Sentinel reports.

Achane has missed three consecutive practices due to a shoulder injury and will be considered a game-time decision for Week 18, per Omar Kelly of the Miami Herald. With the Dolphins already eliminated from playoff contention, the team may opt to err on the side of caution with the health of Achane, who arguably is the club's top playmaker on offense. He hasn't yet missed a game in 2025, and across 16 regular-season appearances the undersized ball carrier leads Miami's offense with 1,838 yards from scrimmage, which is fifth most in the NFL. If Achane is inactive Sunday, Jaylen Wright likely will start out of the backfield while Ollie Gordon and new signee Donovan Edwards contribute in depth roles. Achane's status will be made official no later than 90 minutes prior to Sunday's 4:25 p.m. ET kickoff.

Jacobs (knee/ankle) doesn't have an injury designation for Sunday's game against the Vikings.

Jacobs may or may not actually play, with the Packers expected to hold out QB Jordan Love (and potentially other starters) in preparation for the playoffs. He's 71 rushing yards away from reaching 1,000 for the season, but it's a big ask against a tough Minnesota defense with Clayton Tune under center for Green Bay.

Hunt (illness) doesn't carry an injury designation for Sunday's season finale against the Raiders after practicing fully Friday.

Hunt logged 'DNPs' Wednesday and Thursday, but the running back's full participation in Friday's session sets the stage for him to be available Week 18. Meanwhile, fellow RB Isiah Pacheco (not injury-related/rest) is listed as questionable to face Las Vegas, and if he's made inactive this weekend, Hunt would be in a position to lead a Kansas City backfield that also includes Brashard Smith and Dameon Pierce. In his last outing, Hunt logged a 56 percent snap share en route to rushing seven times for 38 yards in the Chiefs' Week 17 loss to the Broncos, while Pacheco carried nine times for 32 yards, seeing action on 35 percent of the team's snaps on offense.

Mafah (shoulder), who remains on injured reserve, is listed as questionable for Sunday's contest at the Giants, Jon Machota of The Athletic reports.

The Cowboys ruled out top two RBs Javonte Williams (shoulder/neck) and Malik Davis (calf/eye) for Week 18 on Friday, leaving Jaydon Blue as the only healthy option at the position on the active roster. If Mafah is activated from IR on Saturday afternoon ahead of Sunday's matchup, he'll at least be available to Dallas' backfield. A 2025 seventh-round pick, Mafah spent the entire regular season through Week 17 on injured reserve and thus is awaiting his first snaps as a pro.

Davis (eye/calf) and Javonte Williams (neck/shoulder) have been ruled out for Sunday's game at the Giants, Jon Machota of The Athletic reports.

Davis reportedly still can't see well after taking a blow to the eye during last week's win over Washington. He finished the game with 20 carries for 103 yards, both career highs, arguably making him the favorite for the No. 2 RB role in Dallas next year. Williams is scheduled for free agency, but the Cowboys likely will re-sign him or pursue a replacement. The 27-year-old Davis has some parallels to Rico Dowdle, who also lingered around the Dallas roster and practice squad for years before getting his shot as the No. 2 RB, which he later parlayed into a starting job.

Pacheco (rest) is listed as questionable for Sunday's game in Las Vegas.

Pacheco was listed as limited on all three of the Chiefs' Week 18 injury reports with rest, while fellow RB Kareem Hunt didn't practice Wednesday or Thursday due to an illness before returning to a full session Friday. Having said that, Pacheco is entering the weekend with a designation, and Hunt is not. Kansas City is out of playoff contention, so the team may opt to rest Pacheco, but such a decision doesn't need to be made until about 90 minutes before Sunday's 4:25 p.m. ET kickoff. If Pacheco is inhibited or sidelined this weekend, Hunt, Brashard Smith and Dameon Pierce would be lined up to handle the backfield.

Williams (shoulder/neck) has been ruled out for Sunday's game at the Giants, Jon Machota of The Athletic reports.

With fellow running back Malik Davis (eye) also ruled out, Dallas likely will turn to rookies Jaydon Blue and Phil Mafah (shoulder). Mafah is listed as questionable after upgrading to full practice participation Friday, seemingly on track to be activated from injured reserve by Saturday afternoon. There hasn't been any indication that Williams' neck/shoulder injury is a long-term concern, but there's no reason to risk it on the eve of free agency. The Cowboys have publicly expressed interest in re-signing Williams after his breakout campaign on a one-year contract.

Brown (illness) doesn't have a designation for Sunday's game versus the Browns.

Brown sat out practice Wednesday and Thursday due to an illness, but his return to the field Friday included no limitations, thereby clearing him to continue to lead the Bengals backfield Week 18. Since the team's Week 10 bye, he's reeled off 745 yards from scrimmage and seven total TDs in seven contests, and with QB Joe Burrow starting and no other key skill-position players expected to have a reduced workload Sunday, Brown should be good for his typical 60-plus percent snap share.