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D'Andre Swift RB | CHI
Lions' D'Andre Swift: Won't return to Thursday's contest
Swift (shoulder) will not return to Thursday's game against the Bears.
With Swift ruled out for the rest of the contest, Jamaal Williams now is in line to head the Lions backfield in his absence. Swift now will target a potential return to action Week 13, when Detroit faces Minnesota on Sunday, Dec. 5.
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Jake Bargas RB | NO
Jake Bargas: Returns to practice squad
The Vikings restored Bargas to the practice squad from the practice squad COVID-19 list.
Bargas spent the requisite 10 days on the list but is good to go now. He has played in one game in his career, which was Week 16 of 2020, but he registered no stats.
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Cordarrelle Patterson RB | PIT
Falcons' Cordarrelle Patterson: Reps capped in practice
Patterson (ankle) was a limited participant in Thursday's practice, Scott Bair of the Falcons' official site reports.
Patterson was also listed as limited on Wednesday's practice report, and after sitting out the Falcons' Week 11 loss to the Patriots, he may need to upgrade to full activity Friday in order to approach Sunday's game in Jacksonville without a designation. While Patterson was sidelined for the 25-0 loss to New England, practice-squad callup Qadree Ollison was the surprise leader in the Atlanta backfield with nine carries for 34 yards.
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Jermar Jefferson RB | ARI
Lions' Jermar Jefferson: Cleared to suit up Thursday
Jefferson (ankle/knee) is active for Thursday's game against the Bears.
After sitting out the Lions' Week 11 loss to the Browns on account of the two lower-body injuries, Jefferson was listed as a limited participant on each of the team's three practice reports issued Monday through Wednesday. That was enough for him to take a questionable designation into the Thanksgiving Day matchup and ultimately gain clearance ahead of the 12:30 p.m. ET kickoff. In his last appearance Week 10 in Pittsburgh, Jefferson carried three times for 41 yards and a touchdown before departing with the injury, but he could be at risk of falling out of the offensive game plan entirely. No. 2 back Jamaal Williams was sidelined against Pittsburgh due to injury, but he returned to action last week and should rank as the preferred option for complementary duties behind starter D'Andre Swift.
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Mike Boone RB | MIA
Broncos' Mike Boone: Limited at Wednesday's practice
Boone (hip) was a limited participate at practice Wednesday, George Stoia III of The Denver Gazette reports.
Boone was inactive for the Week 10 loss to the Eagles, but he's back at practice coming out of the bye week. The 26-year-old should be able to avoid an injury designation for this weekend if he can practice fully later in the week.
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JaMycal Hasty RB | NE
49ers' JaMycal Hasty: Doesn't practice Wednesday
Hasty (ankle) was listed as a non-participant on Wednesday's injury report, Keiana Martin of the 49ers' official site reports.
Hasty hasn't practiced since showing up on the 49ers' first Week 10 injury report with the ankle issue. Meanwhile, Elijah Mitchell returned in a limited fashion Wednesday after being held out all of last week and from Sunday's game at Jacksonville upon undergoing surgery on his finger. If Mitchell puts himself in a position to play Week 12 against the Vikings, he should resume his role as San Francisco's No. 1 running back. As for Hasty, he'll have two more sessions to do the same this week, but Jeff Wilson and Trey Sermon are healthy in the event Hasty misses a third consecutive contest.
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Matt Breida RB | SF
Bills' Matt Breida: Carving out backfield role
Head coach Sean McDermott suggested Wednesday that Breida has earned more touches going forward, Nick Wojton of the USA Today reports.
McDermott's brief answer doesn't provide any specific insight into how that will translate into Breida's workload Thursday against the Saints, but over the Bills' last two games, he's provided enough of a spark with his limited touches that it would seem logical the speedster gets a chance to build off that Week 12. However, the continued presence of Devin Singletary and Zack Moss in Buffalo's backfield makes Breida a hit-or-miss lineup consideration, though he's an option for those presently scrambling for backfield help due to injuries or byes.
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D'Onta Foreman RB | CLE
Titans' D'Onta Foreman: Limited at practice Wednesday
Foreman was a limited participant in Wednesday's practice due to a triceps injury, Jim Wyatt of the Titans' official site reports.
Meanwhile, fellow running back Jeremy McNichols (concussion) didn't practice, and with Adrian Peterson no longer in the mix after being waived Tuesday, Dontrell Hilliard currently profiles as the Titans' top healthy backfield option. Assuming Foreman is able to play Sunday against the Patriots, he would be in line to share work with Hilliard, with Rodney Smith a candidate to be elevated from the team's practice squad should McNichols remain sidelined this weekend.
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Tony Jones RB | ARI
Saints' Tony Jones: More work possible Thursday
Jones could be in line for a bigger workload Thursday against the Bills with Alvin Kamara (knee) ruled out and Mark Ingram (knee) questionable for the contest, Larry Holder of The Athletic reports.
Kamara's sprained MCL is forcing him out for a third straight game, while Ingram was listed as limited twice and with no activity once on Saints practice reports during Week 12 prep. If Ingram ends up joining Kamara as inactive Thursday, Jones, special-teamer Dwayne Washington, fullback Alex Armah and wide receiver Ty Montgomery would be the candidates for backfield reps. To date, Jones has gotten the most work among the quartet out of the backfield this season, averaging 3.6 yards on his 22 carries and gathering in four of six targets for 10 yards.