Cook rushed twice for 15 yards and wasn't targeted in Sunday's 35-8 win over the Jets. He finished the regular season with 309 carries for 1,621 yards and 12 touchdowns while adding 33 catches for 291 yards and two touchdowns on 40 targets.

Cook notched carries of 10 yards and five yards on the game's first two plays before watching Ray Davis and Ty Johnson split Buffalo's backfield workload the rest of the way. Despite Cook's limited workload in the regular-season finale, he'll finish as the league leader in rushing yards unless Derrick Henry gains at least 153 rushing yards in Sunday's game against the Steelers. The Bills earned the No. 6 seed in the AFC playoffs and will go on the road against the Jaguars in the wild-card round.

Gibbs rushed 19 times for 80 yards and brought in three of five targets for 33 yards and a touchdown in the Lions' 19-16 win over the Bears on Sunday.

Gibbs led the Lions in rushing yards while also providing his fifth touchdown catch of the season on a 15-yard grab with under five minutes remaining in the first half. The third-year pro bounced back nicely on the ground after several weeks of subpar production, recording his highest rushing yardage tally since his memorable 219-yard effort against the Giants in Week 12. Gibbs put together another stellar campaign in a non-playoff season for Detroit, rushing for 1,223 yards and 13 touchdowns at 5.1 yards per carry while adding a career-best 77-616-5 receiving line across 17 games.

Pollard rushed the ball 14 times for 48 yards in Sunday's 41-7 loss to the Jaguars. He added three receptions on three targets for 17 yards.

Pollard was unable to keep his recent level of play going, falling below 95 yards from scrimmage for the first time since Week 13. He still dominated work out of the Titans' backfield, however, and found enough running room to set a new career high of 1,082 rushing yards for the season. Pollard is set to enter the final year of his current contract with the Titans and is likely to remain the team's lead back in 2026.

Marks carried the ball 10 times for 48 yards and caught two of three targets for zero yards in Sunday's 38-30 win over the Colts.

The Texans wound up sitting many of their starters, including Marks, in the second half as their chances of winning the AFC South slipped away in Jacksonville. As a result, British Brooks led the team with 63 rushing yards. Marks didn't take on a significant role in the Houston offense until Week 4, but the 2025 fourth-round pick still wrapped up his first NFL season with 911 scrimmage yards and five total TDs (two rushing, three receiving) over 16 games. He'll lead the Texans backfield into a wild-card clash with the winner of Sunday's night's AFC North battle between the Ravens and Steelers.

Johnson (coach's decision) is inactive for Sunday night's contest against the Ravens.

Johnson will be a healthy scratch for the third straight week to end the regular season. The Steelers will operate with Jaylen Warren and Kenneth Gainwell as their two options in the backfield versus Baltimore.

Etienne rushed the ball 14 times for 32 yards in Sunday's 41-7 win over the Titans. He added one reception on one target for six yards.

Etienne had a very strong regular season, though Sunday served as a disappointing close. He logged a long rush of 11 yards, but eight of his 14 attempts on the ground picked up two or fewer yards. Etienne was also limited to only one target for just the third time this season and ultimately ended up with limited volume after being pulled early in the fourth quarter. If there was a positive point to note, he was able to surpass 1,100 rushing yards for the first time since 2022, his second season as a pro. Etienne should be in line for a bounce-back effort in the wild-card round, though it is still undetermined who the Jaguars will face.

Taylor carried the ball 14 times for 26 yards and caught both his targets for 13 yards in Sunday's 38-30 loss to the Texans.

It was the least productive game of the season for Taylor, as his longest run went for only eight yards and rookie DJ Giddens wound up leading the Colts with 30 rushing yards. Taylor missed his chance to catch James Cook for the NFL rushing crown, but he still wraps up an impressive campaign with 1,585 rushing yards and a career-high 18 TDs on the ground, along with a 46-378-2 line on 55 targets through the air. The 26-year-old RB will head into 2026 as the centerpiece of the Indianapolis offense.

Brown carried the ball 13 times for 72 yards and caught four of six targets for 18 yards and a touchdown in Sunday's 20-18 loss to the Browns.

The rushing yardage gave Brown his first 1,000-yard campaign on the ground, while the first-quarter TD gave him a total of 11 on the season (six rushing, five receiving) to tie his career high. The third-year RB also set a new personal best with 1,456 scrimmage yards, and he'll head into the final year of his rookie contract in 2026 locked into the top spot in the Cincy backfield.

Sampson carried the ball 10 times for 32 yards and caught two of three targets for 12 yards in Sunday's 20-18 win over the Bengals.

Making his second straight start with Quinshon Judkins (ankle) done for the year, Sampson wasn't able to get much going, with his longest gain of the day going for only 11 yards. The 2025 fourth-round pick wraps up his first NFL campaign with 446 scrimmage yards and two touchdowns, both through the air, on 98 touches over 15 games. Assuming Judkins is healthy for the beginning of next season, Sampson figures to work behind him, primarily on passing downs.

Blue rushed 16 times for 64 yards and a touchdown but wasn't targeted in the passing game during Sunday's 34-17 loss to the Giants.

Blue spent most of his rookie season as a healthy inactive, but he took on the lead-back role in the regular-season finale as the Cowboys played without Javonte Williams (shoulder) and Malik Davis (eye/calf). Blue made the most of his opportunity, scoring his first NFL touchdown on a 14-yard run in the first quarter. The 2025 fifth-round pick will try to carve out a larger role in his second NFL campaign after dressing for only five games as a rookie. Blue had 38 carries for 129 yards and one touchdown while catching his only target for five yards across those five appearances.