Knight exited Sunday's game at Houston due to an ankle injury, Darren Urban of the Cardinals' official site reports.

Knight had his left ankle pinned under a Texans defender as he was tackled to the turf early in the first quarter. Per Urban, Knight was carted to the locker room and soon after was deemed questionable to return. Michael Carter and Emari Demercado are left as the likeliest candidates to carry Arizona's backfield for as long as Knight is sidelined.

Marks is expected to serve as the Texans' lead back in Sunday's game against the Cardinals due to Nick Chubb (ribs) being inactive for the contest, Sam Warren of the Houston Chronicle reports.

Warren notes that Houston could have Dare Ogunbowale and Jawhar Jordan mix in for reps out of the backfield, but the lion's share of touches and snaps will likely fall to Marks. After Chubb departed early in this past Sunday's 20-10 win over the Chiefs, Marks finished with an 87 percent offensive snap share and produced 76 total yards and a touchdown on a season-high 28 touches.

McNichols is in line for more work Sunday at the Giants with Chris Rodriguez (groin) inactive for the contest.

Rodriguez logged a pair of limited practices during Week 15 prep due to a groin issue, and after being listed as questionable ahead of the weekend, he'll get at least one week off to focus on his rehab. His 55 touches from the past five outings thus are available, but Jacory Croskey-Merritt seems likeliest to benefit on early downs, while McNichols serves in a change-of-pace role. McNichols is averaging 3.8 touches for 27.8 yards from scrimmage per game while scoring one rushing TD in 13 appearances on the campaign.

Croskey-Merritt is in line for an increased workload Sunday at the Giants with Chris Rodriguez (groin) inactive for the contest.

Rodriguez managed a pair of limited practices during Week 15 prep due to a groin injury, and after being listed as questionable ahead of the weekend, he'll get at least one week off to focus on his recovery. His 55 touches from the last five games thus are up for grabs, and Croskey-Merritt is the likeliest to benefit in the Commanders backfield due to his ability to handle early downs, while Jeremy McNichols serves as a change-of-pace option. A rookie seventh-round pick, Croskey-Merritt has averaged 4.4 yards per carry and 7.6 yards per catch among his 134 touches in 13 games to begin his career.

Chubb (ribs) is inactive for Sunday's game against the Cardinals.

Though Chubb has a lengthy injury history, he had played in each of the Texans' first 14 games of the season before exiting last Sunday's win over the Chiefs due to the rib injury. He was unable to practice Wednesday and Thursday before returning to practice Friday as a limited participant, prompting the Texans to list him as questionable heading into the weekend. Ultimately, Chubb wasn't able to make enough progress to give it a go Sunday, so his absence should clear the way for rookie Woody Marks to serve as Houston's lead option out the backfield. Dare Ogunbowale, Jawhar Jordan and British Brooks will provide depth behind Marks.

Demercado (ankle) is listed as active Sunday at Houston.

Demercado thus is in line for his first game action since he initially suffered a high-ankle sprain during Week 11 at San Francisco. He'll join healthy backfield mates Bam Knight and Michael Carter in Week 15. In the four games in which all three have received offensive snaps this season, Demercado has totaled 18 touches to Knight's 37 and Carter's 44, which would seem to indicate Demercado will be third in the pecking order for reps, especially given that he didn't log a full practice in advance of his return.

Rodriguez (groin) is listed as inactive Sunday at the Giants.

After being held out of Wednesday's practice due to a groin injury, Rodriguez capped Week 15 prep with back-to-back limited sessions, leaving him questionable for Sunday's game. With his lack of availability now confirmed, Rodriguez's workload from the last five contests (55 touches) likely will be split between Jacory Croskey-Merritt (45 during that span) and Jeremy McNichols (22), while Chase Edmonds also is on hand. Rodriguez's next chance to suit up is next Saturday against the Eagles.

Wilson (illness), who is questionable for Sunday's Week 15 matchup against Denver, will see how he feels in the morning before a determination is made about his availability, Adam Schefter of ESPN reports.

Per Schefter, Wilson showed up at Green Bay's training facility with a virus Saturday and was sent home with medication. While the team hopes the running back has recovered enough to play Sunday, it sounds like that decision won't be made until he checks in with the Packers early Sunday. Starting RB Josh Jacobs (knee) is expected to suit up against Denver, according to Schefter, but if Wilson sits out, more carries could be available for Chris Brooks and practice-squad elevation Pierre Strong.

Chubb (ribs), who is officially questionable to play against the Cardinals on Sunday, is not expected to suit up, Adam Schefter of ESPN reports.

Chubb suffered an injury to his ribs last Sunday night against Kansas City and missed the first two days of practice this week. He advanced to a limited session Friday to draw a questionable tag, but it doesn't look like that will be enough for the veteran running back to take the field against Arizona. Woody Marks should dominate backfield work for Houston, while Dare Ogunbowale is slated for an uptick in offensive snaps as the team's No. 2 ball carrier.

Demercado, who is officially questionable for Sunday's game against Houston due to an ankle injury, is expected to play, Adam Schefter of ESPN reports.

Demercado hasn't been able to play in any of Arizona's past three games due to the ankle issue, but he logged a trio of limited practices this week to set up his return to action. He could take on a fairly significant role right away upon his return, though it's unclear how the Cardinals will split up the workload between Bam Knight, Michael Carter and Demercado. The outlook for the trio isn't particularly bright against a Texans defense that is tied for the fourth-fewest rushing yards allowed to RBs this season.