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Jayden Reed WR | GB
Packers' Jayden Reed: Returns to practice
Reed (collarbone) returned to practice Friday, opening his 21-day window to be activated from injured reserve, Matt Schneidman of The Athletic reports.
Reed presumably won't play Sunday against the Vikings and can be considered uncertain to face the Lions four days later on Thanksgiving Day. The timing of his return to practice suggests he'll be ready for a Dec. 7 matchup with the Bears (Week 14), if not the Thanksgiving game.
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Sean Tucker RB | TB
Buccaneers' Sean Tucker: Could lead Irving-less RB room
Tucker is poised to play a significant role Sunday against the Rams, as Scott Smith of the Buccaneers' official site reports that Bucky Irving (shoulder/foot) won't play.
Irving has been sidelined since Week 4. Rachaad White led Tampa Bay's backfield for the majority of Irving's absence, but Tucker has pulled ahead of White in recent weeks, and Tucker cemented his spot as the top fill-in option with 140 scrimmage yards and three total touchdowns on 21 touches in Week 11 against the Bills. Replicating that production will be difficult Sunday against the Rams' stout defense, but Tucker's likely to lead Tampa Bay's backfield in touches, with White remaining involved to some extent.
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Paulson Adebo CB | NYG
Giants' Paulson Adebo: Missing fifth straight game
Adebo (knee) won't play Sunday against the Lions, Dan Duggan of The Athletic reports.
Adebo will miss a fifth consecutive game due to a sprained MCL in his knee. His next chance to play will be Dec. 1 against the Patriots. More playing time could be available for Jarrick Bernard-Converse and Korie Black against the Lions in Adebo's absence.
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Kayvon Thibodeaux LB | NYG
Giants' Kayvon Thibodeaux: Remains sidelined in Week 12
Thibodeaux (shoulder) won't play Sunday against the Lions, Dan Duggan of The Athletic reports.
Thibodeaux will miss a second consecutive game, diminishing the Giants' pass rush against Jared Goff and the Lions. The 2022 first-round draft pick's next chance to play will come Dec. 1 against the Patriots. Thibodeaux has just 2.5 sacks in 2025, with none coming since Week 4.
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Chris Godwin WR | TB
Buccaneers' Chris Godwin: Trending toward playing
Buccaneers coach Todd Bowles confirmed Friday that Godwin (fibula) is on track to play Sunday against the Rams, Greg Auman of Fox Sports reports.
It nonetheless remains to be seen if Godwin will avoid a game designation on the final injury report. He was a full practice participant Thursday for the first time since early October.
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Thomas Fidone II TE | NYG
Giants' Thomas Fidone: Ruled out for Week 12
Fidone (foot) won't play Sunday against the Lions, Dan Duggan of The Athletic reports.
Fidone has dealt with a foot injury throughout the season. The special teams contributor's next chance to play will come Dec. 1 at New England.
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Dillon Gabriel QB | CLE
Browns' Dillon Gabriel: Practicing but still in protocol
Gabriel (concussion) is practicing Friday, but he has yet to fully clear the NFL's five-step concussion protocol, Mary Kay Cabot of the Cleveland Plain Dealer reports.
Shedeur Sanders has already been declared the starting quarterback for Sunday's game against the Raiders, but Gabriel still has a chance to be available in a backup role. Gabriel would have to clear concussion protocol to be active Sunday, which would involve practicing without limitations Friday and subsequently gaining clearance from an independent neurologist. If Gabriel's ultimately ruled out, Bailey Zappe would likely work as Sanders' backup Sunday.
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Bucky Irving RB | TB
Buccaneers' Bucky Irving: May return next week
Irving (shoulder/foot) won't play Sunday at the Rams, but Buccaneers coach Todd Bowles said Friday that the running back is trending toward a return Week 13 against Arizona, Greg Auman of Fox Sports reports.
The Buccaneers have listed Irving as a limited participant in five straight practices, dating back to the beginning of last week. He'll miss another game, but he's reportedly making progress, and Bowles even acknowledged recent rumors by telling reporters that Irving "didn't handle it well" when he was unable to practice or play. The implication seems to be that everything is going better now, though Irving will miss at least one more game when the Bucs face the Rams on Sunday night. Sean Tucker figures to get most of the carries after his three-TD outing last Sunday at Buffalo, with Rachaad White also having a role and likely taking most of the passing-down snaps.
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Joe Burrow QB | CIN
Bengals' Joe Burrow: Week 12 status TBD
Burrow (toe) will be listed as questionable for Sunday's game against the Patriots, Kelsey Conway of The Cincinnati Enquirer reports.
Coach Zac Taylor noted that at this stage the Bengals have yet to determine their Week 12 starter at QB. In any case, in order for Burrow to have a chance to face New England on Sunday, he would have to be activated from IR by Saturday afternoon. If Burrow isn't ready to return to the lineup, however, Joe Flacco (right shoulder) would be in line to get the nod versus the Patriots, assuming he's available after being limited at practice Wednesday and Thursday.
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Jermar Jefferson RB | MIN
Cardinals' Jermar Jefferson: Signed to active roster
The Cardinals signed Jefferson to their active roster Friday, Darren Urban of the Cardinals' official site reports.
It's not a good sign for Trey Benson (knee) being activated from injured reserve this week, though the Cardinals also have other injury concerns in the backfield, with Emari Demercado (ankle) ruled out and Bam Knight expected to play through an ankle injury of his own. Jefferson has been with Arizona's practice squad since the beginning of October, but he won't necessarily get touches even if he's active Sunday against the Jaguars.