NFL Player News

Collins (knee) did not practice Wednesday, Eric Branch of the San Francisco Chronicle reports.

Collins suffered a knee sprain in Thursday's win over the Rams, so it's not a big surprise that he was unable to practice to begin preparation for a Week 6 matchup against Tampa Bay. Kalia Davis (hand) will also be sidelined, so the 49ers' defensive line could be shorthanded.

Dean (hip) was a limited participant in Wednesday's practice.

Dean sustained a hip injury during the Bucs' Week 4 loss to the Eagles. He was unable to practice before being ruled out for Week 5 against the Seahawks, so his ability to participate in Wednesday's session -- albeit in a limited capacity -- is a step in the right direction for the 2019 third-rounder. Dean's practice participation over the next two days will indicate his chances of playing against the 49ers on Sunday.

McCollum (thumb) didn't practice Wednesday.

McCollum suffered a thumb injury during the Buccaneers' Week 4 loss to the Eagles. He was able to play against the Seahawks in Week 5 but has since undergone a procedure for the injury, which puts him in jeopardy of missing Sunday's game against the 49ers. McCollum's practice participation over the next two days will shed light on his odds of playing Sunday, but his absence would open the door for Kindle Vildor, Josh Hayes and rookie second-rounder Benjamin Morrison (hamstring) to see additional snaps on defense.

Stout (ankle) was a limited practice participant Wednesday, Eric Branch of the San Francisco Chronicle reports.

Stout suffered a sprained ankle in Thursday's win over the Rams and was considered day-to-day at the time. His ability to practice at all is a positive sign, but his status for San Francisco's Week 6 game against Tampa Bay remains unclear.

Smith (knee) was a limited participant at practice Wednesday, Jon Machota of The Athletic reports.

Smith was active in Week 5 against the Jets, but he remained on the sidelines all day due to the knee injury. He'll get two more opportunities during the week to manage a full practice ahead of Sunday's game at Carolina.

David (knee) was a limited participant in Wednesday's practice.

David has managed lower-body injuries since training camp, though he's played in each of the first five games of the regular season and has logged 34 tackles (17 solo), including 1.5 sacks, and two pass defenses (one interception). David should be cleared to play against the 49ers on Sunday unless he suffers a setback in the coming days.

Mustapha (knee) practiced fully Wednesday, Eric Branch of the San Francisco Chronicle reports.

Mustpaha is recovering from a torn ACL and had his practice window opened Monday. He has three weeks to be activated from injured reserve, so while his full practice participation is a positive sign, it's not indicative that Mustapha will be ready for his season debut in Week 6 against Tampa Bay.

Walker (quadriceps) was a limited participant in Green Bay's practice Wednesday.

Walker managed to play through his injury in the team's Week 4 tie versus Dallas and will look to do the same in Sunday's matchup against the Bengals. However, if he ends up being unable to suit up, the Packers could be shorthanded along the offensive line as Zach Tom (oblique), Anthony Belton (ankle) and Aaron Banks (groin) are all dealing with injuries.

Watkins (calf) did not practice Wednesday, Eric Branch of the San Francisco Chronicle reports.

Watkins has dealt with ankle and calf injuries, and has been sidelined for his entire rookie season to this point. His inability to practice doesn't bode well for his chances to be active in Week 6 against the Buccaneers, though he has a few days to change his outlook.

The 49ers designated Givens (pectoral) to return from injured reserve Wednesday.

Givens suffered a pectoral injury in early August during training camp, which was severe enough for him to open the 2025 regular season on injured reserve. He's progressed enough in his recovery for the 49ers to open his 21-day practice window, and the seventh-year defensive tackle was a limited participant in Wednesday's session, per Eric Branch of the San Francisco Chronicle. Even with his return to practice, Givens is far from a guarantee to play against the Buccaneers on Sunday.