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Xavier Weaver WR | ARI
Cardinals' Xavier Weaver: Draws first target of season
Weaver played 14 of the Cardinals' 67 snaps on offense and failed to corral his lone target in Thursday's 23-20 loss to the Seahawks.
Active for just the second time all season, Weaver served as the Cardinals' No. 4 wideout while Zay Jones (concussion) was sidelined. The 24-year-old is in the midst of his second season in Arizona but has yet to record his first NFL reception. If Jones is able to clear concussion protocol ahead of Sunday's game against the Titans, Weaver could find himself back on the Cardinals' inactive list.
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Teagan Quitoriano TE | ARI
Falcons' Teagan Quitoriano: No targets through four games
Quitoriano went without a target while playing eight of 65 snaps on offense Sunday in the Falcons' 34-27 win over the Commanders.
Quitoriano has been active as the Falcons' No. 3 tight end through each of the first four games of the season but has seen just as much playing time on special teams as offense. He has yet to draw a target and will continue to function mostly as a blocker when he takes the field with the offense.
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Shedeur Sanders QB | CLE
Browns' Shedeur Sanders: Remains third on depth chart
Sanders will remain the Browns' No. 3 quarterback for Sunday's game against the Vikings in London, while Dillon Gabriel moves into the starting role and Joe Flacco serves as his top backup, Adam Schefter of ESPN reports.
Though Flacco will head to the bench after going 1-3 as a starter and averaging just 5.1 yards per attempt and posting a 2:6 TD:INT through the Browns' first four games, he's still on track to remain active Sunday as Gabriel's top understudy. With that in mind, Sanders is poised to be a healthy inactive for the fifth straight game as the team's emergency No. 3 quarterback, though he could eventually usurp Flacco for the No. 2 role or potentially supplant Gabriel as the starter later on in the season.
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Jordan Watkins WR | SF
49ers' Jordan Watkins: Not yet practicing
Watkins (calf) was a non-participant in Tuesday's walk-through practice.
Watkins hasn't practiced in any fashion since Sept. 18 and appears likely to miss a third straight game due to injury Thursday against the Rams. The fourth-round rookie wideout previously missed Week 1 while recovering from a high ankle sprain, then was a healthy inactive for Week 2 before injuring his calf in practice.
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Andrei Iosivas WR | CIN
Bengals' Andrei Iosivas: One grab against Broncos
Iosivas secured his lone target for 22 yards and rushed once for five yards in Monday's 28-3 loss to the Broncos.
Iosivas played 43 of the Bengals' 48 offensive snaps, behind Ja'Marr Chase (46) and ahead of Tee Higgins (40). The wideout's 90 percent snap share was a high mark so far this season. Through four games, Iosivas has recorded just two catches for 34 yards on six targets. Despite his increase in playing time, the third-year receiver should remain far off the fantasy radar on a struggling offense with quarterback Jake Browning at the helm. Next up for the Bengals is a matchup against the Lions in Week 5.
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Samaje Perine RB | CIN
Bengals' Samaje Perine: One carry in loss
Perine rushed once for four yards and failed to secure his lone target in Monday's 28-3 loss to the Broncos.
Perine played 15 of the Bengals' 48 offensive snaps Monday, while starting running back Chase Brown was on the field for 35 snaps. Operating as the clear backup, the 30-year-old Perine was unable to do much of anything with his limited opportunities. Barring an injury to Brown, Perine doesn't hold much fantasy value on a struggling offense. The Bengals are set to host the Lions in Week 5.
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Isaiah Likely TE | NYG
Ravens' Isaiah Likely: Not targeted in season debut
Likely failed to draw a target in Sunday's 37-20 loss to the Chiefs.
Making his season debut after missing the Ravens' first three games while recovering from foot surgery, Likely played 25 of the Ravens' offensive snaps Sunday, just behind fellow tight end Mark Andrews (30). Though the 25-year-old Likely was a non-factor in Baltimore's aerial attack, Andrews drew a team-leading eight targets in the contest. Likely should certainly see his role grow as he gets acclimated coming off the injury, but his chances of making an impact Week 5 versus Houston could be inhibited with starting quarterback Lamar Jackson (hamstring) at risk of missing the contest.
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Devontez Walker WR | BAL
Ravens' Devontez Walker: Not involved in loss
Walker failed to record a single target in Sunday's 37-20 loss to the Chiefs.
Walker was not a part of the Ravens' offensive plans Sunday, as the wideout played just four of the team's 54 offensive snaps in the contest and was held without a target for the second time this season. Buried on Baltimore's wide receiver depth chart, the second-year wideout should continue to face an uphill battle for meaningful playing time. Barring injuries, Walker should not be trusted for fantasy purposes heading into a Week 5 matchup against the Texans.
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Tylan Wallace WR | CLE
Ravens' Tylan Wallace: Records one catch against Chiefs
Wallace caught one of two targets for 14 yards in Sunday's 37-20 loss to the Chiefs.
Wallace played 40 percent of Baltimore's offensive snaps Sunday, his lowest snap share since Week 1. The veteran wideout has had a quiet start to the season, recording just three receptions for 39 yards and a touchdown on five targets. Wallace's limited usage should continue to keep him far off the fantasy radar heading into Week 5 when the Ravens host the Texans.
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Joe Flacco QB | CIN
Browns' Joe Flacco: Moving to backup role
Flacco is slated to back up Dillon Gabriel in Sunday's game against the Vikings, Mary Kay Cabot of The Cleveland Plain Dealer reports.
With the Browns off to a 1-3 start, a span in which Flacco threw six interceptions, the team will pivot to Gabriel, the No. 94 overall pick in the 2025 NFL Draft. In the wake of the move, Flacco will serve as the team's No. 2 signal-caller, while Shedeur Sanders will continue to be the third-stringer, per Adam Schefter of ESPN.