NFL Player News

Williams (knee) does not have any injury designation ahead of Sunday's game against the Falcons.

Williams started Week 7 prep as a non-participant but gradually worked his way up to full practice in Friday's session. The defensive end has overcome his knee injury in time to suit up for Sunday's game opposite Keion White.

Whittington could operate in an expanded role offensively if Puka Nacua (calf, questionable) cannot play against the Raiders on Sunday.

Davante Adams (hamstring) is on injured reserve, so quarterback Matthew Stafford would be without his top targets in the passing game if Nacua is also ruled out. In that event, Whittington, Konata Mumpfield and Tutu Atwell would likely operate as the top-3 wideouts for Sunday's game, with tight end Tyler Higbee also in the mix for more targets. Whittington has only three targets through five regular-season games, which he's turned into two catches for 12 yards.

Holani is slated to remain Seattle's No. 2 running back Sunday against Kansas City, as Zach Charbonnet (knee) has been ruled out for the contest, John Boyle of the team's official site reports.

Charbonnet was activated from the PUP list Thursday and practiced in full all week, but he's not quite ready to make his return from a torn ACL. As such, Holani will log another week as the Seahawks' backup running back behind Emanuel Wilson. That role hasn't led to much production, as Holani has tallied just 97 yards and one touchdown on 31 carries through six games this season, though he's also registered an 11-76-0 receiving line. Should Charbonnet return Week 8 versus Chicago, Holani seems likely to see his opportunities decrease.

Stout (shoulder) is listed as questionable for Sunday's game against the Falcons.

Stout logged consecutive DNPs to begin Week 7 prep before upgrading to a limited participant in Friday's session. The last-minute practice participation has given the cornerback a chance to recover from his AC Joint issues in time for Sunday's contest, but it remains uncertain if the 24-year-old will suit up. If Stout cannot play, Ashtyn Davis will likely start at slot cornerback in his place.

Alie-Cox will operate in an expanded role against the Vikings on Sunday due to the absence of Tyler Warren (groin), Abby Halpin of the Colts' official site reports.

Alie-Cox and Will Mallory will both operate as the top tight ends for Sunday's contest in the absence of Warren, who is missing a second-straight game due to a groin injury. Alie-Cox saw only one target in a Week 6 loss to the Titans, but he made that one catch count for a one-yard score in the first quarter.

Sigle (ankle) has been ruled out ahead of Sunday's game against the Falcons.

Sigle managed to upgrade to a limited participant in Friday's practice after missing consecutive sessions to start Week 7 prep. The strong safety's last-minute upgrade in participation level was not enough to enable him to suit up for Sunday's game, leaving Malik Mustapha as a starter in the 49ers' secondary for a third consecutive week.

Mallory will once again operate in an expanded role after Tyler Warren (groin) was ruled out ahead of Sunday's game against the Vikings, Abby Halpin of the Colts' official site reports.

Warren will end up missing a second consecutive game while battling a groin injury, so Mallory and Mo Alie-Cox will serve as the Colts' top tight ends for Sunday's contest. Mallory turned six targets into two catches for 20 yards in a Week 6 loss to the Titans, and he finished that contest third in targets behind Keenan Allen (11) and Josh Downs (eight).

McLaughlin's role in the offense will sharply decrease against the Titans on Sunday, as Quinshon Judkins (ankle) has been cleared to play and Dylan Sampson (knee) is expected to be activated off injured reserve, Daniel Oyefusi of ESPN.com reports.

McLaughlin turned 13 touches (nine carries, four catches) into 55 yards in a Week 6 win against the Browns, but Cleveland was without Judkins, Sampson and Raheim Sanders (hip) for that contest. With Judkins and Sampson both on track to play Sunday, McLaughlin and Audric Estime will revert to depth roles on offense and will likely be limited to work on special teams.

Dugger (knee) does not have any injury designation ahead of Sunday's game against the Falcons.

Dugger started Week 7 prep with consecutive limited practices before upgrading to a full participant in Friday's session. The strongside linebacker is all set to suit up for Sunday's game against the Falcons opposite Dre Greenlaw.

Watkins could take on a significant role Sunday against Atlanta with Mike Evans (Achilles) and Deebo Samuel (hamstring) both sidelined, Brooke Evans of the 49ers' official site reports.

Watkins already saw a big jump in participation this past Monday versus Washington, tallying a season-high 76 percent offensive snap share in Samuel's absence. However, he drew just one target, which he caught for a 22-yard gain. Now that Evans will also be out of action, Watkins seems likely to be deployed often again Sunday, though Brandin Cooks and Jacob Cowing should also get opportunities to step into larger roles. Finally, Christian Kirk (calf), who is currently on IR, may be activated ahead of the matchup versus Atlanta, and he could also factor into the equation in what would be his 49ers debut.