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Brock Purdy QB | SF
49ers' Brock Purdy: Officially limited in return to practice
Purdy (left shoulder/toe) officially was a limited practice participant Wednesday, Matt Barrows of The Athletic reports.
Purdy fulfilled coach Kyle Shanahan's expectation for his activity level from earlier Wednesday, per Eric Branch of the San Francisco Chronicle. During the media-access portion of the session, Purdy was third in the QB rotation behind Mac Jones and Adrian Martinez, according to Cam Inman of The San Jose Mercury News, and he was seen making throws and also jogging on what has been described as a turf toe variant, per Branch. Purdy thus seemingly has a chance to return to action Sunday versus the Cardinals, but how he fares Thursday and Friday will be telling for his Week 3 availability. Mac Jones will continue to start as long as Purdy is sidelined.
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Ben Bartch OT | DET
49ers' Ben Bartch: Lands on IR
Bartch (ankle) was placed on injured reserve Wednesday, Noah Furtado of the San Francisco Chronicle reports.
Bartch suffered an ankle injury in Week 2 that was originally expected to cost him a few games. He'll now be forced to miss the next four contests, potentially lining up seventh-round rookie Connor Colby to start at left guard for the 49ers.
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Theo Jackson S | MIN
Vikings' Theo Jackson: Limited at practice
Jackson (hip) was a limited participant at practice Wednesday.
Jackson appears to have picked up a hip injury in the team's 22-6 loss to Atlanta in Week 2. His ability to practice in any capacity Wednesday is a positive sign, and he'll look to log a full practice session prior to Sunday's contest versus the Bengals.
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Julian Love SAF | SEA
Seahawks' Julian Love: Tending to hamstring injury
Love (hamstring) did not participate at practice Wednesday, John Boyle of the Seahawks' official site reports.
Love played all 59 of Seattle's defensive snaps in Week 2, so it's not immediately clear when he picked up the hamstring issue. In any case, he'll likely need to practice in some capacity Thursday or Friday to have any chance of playing Sunday versus the Saints.
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Trevon Diggs CB | SEA
Cowboys' Trevon Diggs: Absent from practice walk-through
Diggs (illness) was estimated as a DNP Wednesday, Jon Machota of The Athletic reports.
Diggs saw his snap rate jump to a normal level in Week 2 against the Giants, as he was on the field for 91 percent of defensive snaps. Though he begins the week unable to practice, there's no indication he's in danger of missing Dallas' Week 3 matchup against the Bears.
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Ernest Jones LB | SEA
Seahawks' Ernest Jones: Still dealing with shoulder issue
Jones (shoulder) was a limited participant at practice Wednesday, John Boyle of the Seahawks' official site reports.
Jones played through the shoulder injury in Week 2 at Pittsburgh and ended up leading Seattle in tackles, so it's likely the team is just being extra cautious. He could probably avoid carrying an injury designation into the weekend if he can manage a full practice Thursday or Friday.
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Jonathan Greenard LB | PHI
Vikings' Jonathan Greenard: Limited to open week
Greenard (oblique) was a limited participant at practice Wednesday.
Greenard appears to have left the team's 22-6 Week 2 loss to the Falcons a little worse for wear, popping up on the injury report Wednesday with an apparent oblique injury. The linebacker will have two more chances to log a full practice ahead of Sunday's contest in Cincinnati.
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Jauan Jennings WR | MIN
49ers' Jauan Jennings: No practice Wednesday
Jennings (ankle/shoulder) officially didn't practice Wednesday, Matt Barrows of The Athletic reports.
During Week 2 prep, Jennings missed the first two practices before logging a limited session Friday as he tended to a shoulder injury, but it was enough for him to suit up this past Sunday at New Orleans and serve as the 49ers' top wide receiver for fill-in quarterback Mac Jones. On his 10 targets, Jennings hauled in five receptions for 89 yards and one touchdown. Coach Kyle Shanahan termed Jennings day-to-day Monday due to an ankle injury, and with another DNP under his belt to begin this week, it remains to be seen if he'll follow a similar practice regimen to last week and how he'll be listed ahead of Sunday's home opener against the Cardinals.
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Andrew Van Ginkel OLB | MIN
Vikings' Andrew Van Ginkel: Returns to practice
Van Ginkel (concussion) was a limited participant at practice Wednesday.
Van Ginkel was unavailable for the team's 22-6 loss to the Falcons in Week 2 while recovering from a concussion. The linebacker will now have two more opportunities to clear concussion protocol and log a full practice before Sunday's matchup with the Bengals.
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Nate Adkins TE | DEN
Broncos' Nate Adkins: Log full practice Wednesday
Adkins (ankle) was a full participant at practice Wednesday, Aric DiLalla of the Broncos' official site reports.
Adkins has been held back to some extent since he underwent a tightrope procedure to address a sprained ankle back in July, but it now appears he's finally back to full strength and ready to make his 2025 debut. If starting tight end Evan Engram (back) is unable to play Sunday against the Chargers, Adkins could be in line for an expanded role.