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The Milwaukee Bucks (46-34) and the Detroit Pistons (44-36) square off in an Eastern Conference battle on Friday as the regular season nears a close. The Pistons were able to halt their two-game losing streak last time out, defeating the New York Knicks 115-106 on Thursday. Milwaukee has won six consecutive games. On Thursday, the Bucks dominated the New Orleans Pelicans 136-111. Damian Lillard (calf) remains out for the Bucks. Isaiah Stewart (knee) is out for Detroit, with Malik Beasley (illness) listed as questionable.

Tipoff is at 7 p.m. ET from Little Caesars Arena in Detroit, where the home team is 22-18. These teams played twice this season, and Milwaukee won both. Milwaukee beat Detroit 128-107 on Dec. 3. Detroit is the 5.5-point favorite in the latest Bucks vs. Pistons odds from SportsLine consensus, while the over/under for total points scored is 230.5, an increase from opening at 227.5. Detroit is at -202 on the money line (risk $202 to win $100), while Milwaukee is at +167 (risk $100 to win $167). Before locking in any Bucks vs. Pistons picks, make sure to check out the NBA predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the final week of the 2024-25 NBA regular season on a sizzling 155-115 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 21-10 (68%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated Bucks vs. Pistons 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Bucks vs. Pistons:

  • Bucks vs. Pistons spread: Detroit -5.5 at DraftKings Sportsbook
  • Bucks vs. Pistons over/under: 230.5 points
  • Bucks vs. Pistons money line: Detroit -202, Milwaukee +167
  • MIL: The Bucks are 41-38-2 against the spread this season 
  • DET: The Pistons are 42-35-3 against the spread this season 
  • Bucks vs. Pistons picks: See picks at SportsLine
  • Bucks vs. Pistons streaming: FuboTV (Try for free)
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Why the Bucks can cover

Forward Giannis Antetokounmpo consistently uses his strength to overpower opposing players in the lane. Antetokounmpo is second in the NBA in points (30.4) and sixth in rebounds (11.9) and field goal percentage (60.2%). He's posted a triple-double in three of his last four games. In the April 5 win over the Heat, Antetokounmpo had 36 points, 15 rebounds and 10 assists. 

Forward Kyle Kuzma came over to Milwaukee in February and has been a nice scoring threat added to the rotation. He averages 14.8 points, 5.9 rebounds and 2.4 assists per game. On April 6 versus the Pelicans, Kuzma had 17 points, four rebounds and four assists. See which team to back at SportsLine.

Why the Pistons can cover

Guard Cade Cunningham is an impact player in multiple ways. Cunningham is eighth in the NBA in points (25.9) and fourth in assists (9.1). He has racked up 30 double-doubles this season thus far. He's also finished with 25-plus points in five straight games. In Monday's loss to the Kings, Cunningham had 35 points and five dimes.

The Pistons have played very well on back-to-backs this season, going 8-4-2 against the spread on days with no rest. Beasley has been a sharpshooter on the perimeter to space the floor. Beasley averages 16.2 points, 2.7 rebounds and shoots 41.3% from beyond the arc. On April 4 against the Raptors, he had 21 points, four boards and made three 3-pointers. See which team to back at SportsLine

How to make Bucks vs. Pistons picks

SportsLine's model has simulated Bucks vs. Pistons and is leaning Under the total, projecting 222 combined points. The model also says one side of the spread hits in over 50% of simulations. You can head to SportsLine to see the model's NBA picks

So who wins Bucks vs. Pistons, and which side of the spread hits in over 50% of simulations? Visit SportsLine now to see which side of the Bucks vs. Pistons spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out. 

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