DETROIT (AP) Boston Scott and Jordan Howard made the most of filling in for running back Miles Sanders and took advantage of Philadelphia dominating Detroit's defensive line.

Scott and Howard each had two touchdowns on the ground, helping the Philadelphia Eagles run over the Detroit Lions in a 44-6 win Sunday.

''We were able to push some guys around up front,'' coach Nick Sirianni said.

The Eagles (3-5) ended a two-game losing streak against a team that was very accommodating, enjoying their most lopsided win on the road since beating the St. Louis Cardinals by 42 points nearly 40 years ago.

The Lions (0-8) go into their bye week as the NFL's only winless team.

''If this doesn't get better, we're going to be 0-17,'' Detroit safety Tracy Walker said.

The break gives first-year coach Dan Campbell extra time to figure out how to avoid making history during the league's first 17-game schedule after being a tight end on the first 0-16 team in Detroit 13 years ago.

''I can take a week and look at everything,'' Campbell said.

When Campbell looks at film of the latest loss, he will see how inept his lines were on both sides of the ball.

With Sanders on injured reserve with an ankle injury from last week, Scott and Howard had 12 carries each and combined for 117 yards rushing combined. Scott had just seven carries this season before Sunday and Jordan made his season debut after being promoted from the practice squad. They became the first pair of Eagles to run for multiple touchdowns in the same game since 1980.

''Whenever that opportunity knocks, you got to step up,'' Scott said. ''Me and Jordan motivated each other during the time leading up to this moment.''

Scott broke a scoreless tie late in the first period with a 1-yard run and and Howard's 4-yard run late in the second quarter put Philadelphia up 17-0. They each had a short touchdown run in the third quarter.

Just to make the setback sting a little more for the Lions and their fans, former Detroit cornerback Darius Slay scooped up D'Andre Swift's fumble that was forced by Detroit native Avonte Maddox and returned it 33 yards make it 38-0 late in the third.

''It was a blessing,'' Slay wrote in a text message after the game. ''I appreciate how the fans shouted me out and showed major love.''

The offensively challenged Lions avoided a shutout midway through the fourth quarter when rookie Jermar Jefferson scored on an 8-yard run for his first NFL touchdown.

Alas, the Lions failed to convert the 2-point conversion as Jared Goff was hit, as he often was by the Eagles from every direction even when they rushed just four against five offensive linemen.

Goff was sacked a season-high five times and finished 23 of 34 for 222 yards. The sixth-year quarterback and many of his teammates made mistakes, including when he threw a ball away in the third quarter on fourth down instead of throwing toward a receiver with nothing to lose.

''Throwing the ball into the stands on fourth down is a bad decision, but I'm not sure what else he was supposed to do,'' Campbell said.

The Eagles didn't need to pass much to beat Detroit, so they didn't as Jalen Hurts was 9 of 14 for 103 yards. He ran seven times for 71 of his team's 236 yards rushing.

''We got pushed around bad,'' Campbell acknowledged.

JOHNSON SPEAKS

Three-time Pro Bowl right tackle Lane Johnson had his first news conference after the game, his second since returning from a three-game absence related to anxiety and depression.

''The real message is, don't bottle it up,'' he said.

Johnson said he stopped treating his condition with medication, leading to withdrawal symptoms that left him feeling as if he had the flu.

DULL ROAR

The Lions gave their fans something to cheer about when former linebacker Chris Spielman was inducted into the Pride of the Lions. The 1991 All-Pro and four-time Pro Bowl linebacker now has his name displayed at Ford Field along with 18 other former players, including Hall of Famers Barry Sanders and Joe Schmidt.

NOTEABLE

The Eagles had six sacks, including one against David Blough, for the first time in nearly 10 years. Philadelphia had its highest-scoring game since a 51-23 win over Denver nearly four years ago.

INJURIES

Eagles: WR Jalen Reagor had an ankle injury in the first quarter on a touchdown drive he boosted with 11- and 10-yard runs on end-around plays.

Lions: RB Jamaal Williams (thigh) and CB A.J. Parker (neck) were inactive.

UP NEXT

Eagles host Los Angeles Chargers next Sunday.

Lions have their bye next week and are off until Nov. 14 at Pittsburgh.

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