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Commanders running back Brian Robinson Jr. (hamstring) is out for the second straight game and his replacement was once one of the most sought-after running backs for daily Fantasy football players. Austin Ekeler will take a prominent role in Washington's offense again after last week, when the 29-year-old had 83 total yards and a touchdown. The Commanders play the Steelers, who are allowing the fourth-fewest rushing yards (90.5 per game), so should Ekeler factor into your Week 10 NFL DFS strategy? He could be a popular value play for NFL DFS lineups, even going against one of the better defenses in the NFL.

Finding NFL DFS sleepers set to take on a starter's workload are often popular plays for NFL DFS picks. Is that an NFL DFS strategy you should utilize and take that money to add top receivers from the NFL DFS player pool? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine's advanced NFL DFS Lineup Optimizer.

The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool for sports betting apps.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2024 NFL Week 10 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

Top NFL Week 10 DFS picks for Sunday

One of the Optimizer's top DFS value picks for Sunday is Jets wide receiver Garrett Wilson ($7,200 on DraftKings and $7,900 on FanDuel). The 24-year-old is the most-targeted receiver in the NFL at 94 targets and also leads the league in receptions (60) in a pass-heavy offense. New York is throwing on 63.5% of plays, the fifth-most in the NFL, with the Jets showing complete confidence in Aaron Rodgers to run his style of offense. The No. 10 overall pick in the 2022 NFL Draft has at least eight targets in eight of nine games this season as he's a consistent focal point in the offense.

The Cardinals rank 27th in completion percentage allowed (69.1%) this season and Wilson has secured 63.8% of his targets, the highest of his three-year career. Even with the addition of Davante Adams, Wilson has found success with at least 90 yards in back-to-back contests. Wilson had two acrobatic touchdowns last week and his five touchdown receptions are already more than he's had in either of his previous two seasons. Wilson is having a career year with Rodgers and the Optimizer expects the production and usage to continue against Arizona.

The Optimizer's NFL DFS strategy also includes rostering Vikings running back Aaron Jones ($6,700 on DraftKings and $7,900 FanDuel). Jones rushed for 64 yards and added four receptions for 18 yards last week against the Colts. He has been a focal point in the surprisingly efficient Vikings offense this season with more than 90 rushing yards in four of eight games this year.

The Vikings have the No. 8 scoring offense (26.1 points per game) this season ahead of a matchup against the Jaguars, who rank 30th in scoring defense at 28 points per game. The Jaguars are 31st in yards allowed (389.3 per game) and have struggled against running backs. The Jaguars are allowing the third-most Fantasy football points to opposing running backs this season in what could be a slate-breaking performance for Jones. You can see the rest of the Optimizer's NFL DFS picks here.

How to build Sunday Week 10 NFL DFS lineups

The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the Optimizer's NFL DFS picks, at SportsLine

So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS Optimizer that simulates every game 10,000 times, and find out.