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Familiar foes clash in Week 10 as the Florida Atlantic Owls (2-5, 0-3) host the South Florida Bulls (3-4, 1-2) in an AAC showdown on Friday. Both teams are coming off of bye weeks, with the Bulls defeating last-place UAB 35-25 in Week 8 and the Owls falling 38-24 to UTSA. USF's win ended a three-game losing skid, while Florida Atlantic have lost back-to-back games heading into Friday.

Kickoff from FAU Stadium is 7:30 p.m. ET. After opening at -4.5, the Bulls are now 2.5-point favorites in the latest FAU vs. USF odds via SportsLine consensus, while the over/under for total points scored is 47.5, down from opening at 51. Before making any USF vs. FAU picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.  

Now, the model has dialed in on Florida Atlantic vs. South Florida and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football betting lines and trends for South Florida vs. Florida Atlantic.

  • FAU vs. USF spread: Bulls -2.5
  • FAU vs. USF over/under: 47.5 points 
  • FAU vs. USF money line: USF -139, FAU +115
  • FAU: 3-4-0 ATS this season 
  • USF: 3-4-0 ATS this season 
  • FAU vs. USF picks: See picks here
  • FAU vs. USF streaming: FuboTV (Try for free)

Why South Florida can cover

The biggest question mark for the Bulls heading into Friday's game is whether Byrum Brown, who has been out since Sept. 28 with a leg injury, will play, and there is some concern since backup quarterback Bryce Archie has struggled with his accuracy over two starts. Archie did, however, play better against a UAB defense that doesn't give up much in the passing game. Running back Kelley Joiner rushed for 94 yards and had two touchdowns in that game, and he will challenge an FAU rush defense that is allowing 200.7 average yards on the ground.

The Bulls' defense has done well against the run this season, allowing just 137.3 yards per game. It has also faced tough quarterbacks this season in Miami's Cam Ward and Alabama's Jalen Milroe. FAU's offense isn't as potent as those two programs, so South Florida's defense can keep them at bay in an effort to cover the spread. See who to back at SportsLine.

Why Florida Atlantic can cover

The Owls are looking for a bounce-back performance from quarterback Cam Fancher, who completed just 47.4% of his passes in Week 8 against the UTSA Roadrunners. He will have room to improve on Friday against a Bulls passing defense that ranks towards the bottom of the AAC with 291.3 average yards allowed per game. Fancher has also found success contributing to the ground game, which is averaging 153.1 yards per game.

Florida Atlantic has a leg-up in the all-time series, winning the last two meetings against South Florida. That includes a game last season in Tampa that the Owls won 56-14. See who to back at SportsLine.

How to make FAU vs. USF picks

SportsLine's model is leaning Over on the total, projecting 61 combined points. It also says one side of the spread hits in well over 50% of simulations. You can see the model's pick at SportsLine.

So who wins South Florida vs. Florida Atlantic, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.