Holliday will undergo surgery Thursday for a fractured right hamate bone and will begin the season on the injured list, Roch Kubatko of MASNSports.com reports.

A clearer timetable should become available after the operation, but Holliday will shelved for several weeks in any case. Additionally, it's a procedure that can often result in an initial loss of power for a player upon their return. Blaze Alexander and Jordan Westburg (oblique) are candidates to handle second base while Holliday is out.

Gusto (shoulder) will be available to pitch this week as spring training gets underway, Christina De Nicola of MLB.com reports.

Gusto closed the 2025 season on the Marlins' injured list after he was diagnosed with a right shoulder impingement in late August, but he was able to make a full recovery over the offseason. Between his stops with Houston and Miami last season, Gusto started 17 of his 27 appearances and posted a 5.67 ERA and 1.48 WHIP in 101.2 innings. The Marlins could have the right-hander stretch out as a starter during spring training, but he'll likely serve as more of a insurance option for the rotation and could begin the campaign as a long man out of the bullpen.

Garrett (elbow) will be available to pitch this week as spring training gets underway, Christina De Nicola of MLB.com reports.

The Marlins announced Wednesday that aside from Calvin Faucher -- who has yet to report to camp --and the rehabbing Ronny Henriquez (elbow), all pitchers on the 40-man roster are operating with no restrictions to begin camp. Garrett missed the entire 2025 season after undergoing elbow surgery with an internal brace in December 2024, but he told Kevin Barral of FishonFirst.com that he threw "a couple" live bullpen sessions prior to reporting to camp and is scheduled to throw another one Wednesday. Since he's coming off a major injury, Garrett may be eased into Grapefruit League action, but the 28-year-old lefty should have a fairly clear path to an Opening Day rotation spot.

Astros manager Joe Espada announced Wednesday that Brown will be the team's Opening Day starter, Chandler Rome of The Athletic reports.

Most teams don't reveal their Opening Day starters this early in spring training, but Brown was the obvious choice after finishing third in American League Cy Young voting in 2025. The 27-year-old right-hander will go up against the Angels at home on Opening Day.

Meyer (hip) will be available to pitch this week as spring training gets underway, Christina De Nicola of MLB.com reports.

The Marlins announced Wednesday that aside from Calvin Faucher -- who has yet to report to camp --and the rehabbing Ronny Henriquez (elbow), all pitchers on the 40-man roster are operating with no restrictions to begin camp. A healthy Meyer should have the inside track on a spot in the Opening Day rotation. The 26-year-old turned in a 4.73 ERA, 1.42 WHIP and 68:20 K:BB across 64.2 innings over 12 starts in 2025 before he was shut down with a left hip labral injury that required season-ending surgery in late June.

Astros manager Joe Espada said Wednesday that De Los Santos has been shut down due to a right knee strain, Chandler Rome of The Athletic reports.

It's unclear when De Los Santos might be cleared to throw again. The right-hander posted a 4.36 ERA and 62:24 K:BB over 66 innings between Atlanta and Houston in 2025. If healthy, De Los Santos is pegged for a middle relief role in the Astros' bullpen.

Diaz is behind schedule with his running program after suffering a left foot sprain during the Dominican Winter League, Chandler Rome of The Athletic reports.

Diaz is participating in other baseball activities and will catch Tatsuya Imai's bullpen session Wednesday, but he's a tad behind with his running. It does not sound like an injury that will sideline Diaz long, but the Astros could hold him out of the first handful of Grapefruit League games just to be safe.

Manager A.J. Hinch announced Wednesday that Skubal will draw the starting nod for the Tigers' Opening Day game March 26 versus the Padres in San Diego, Evan Petzold of the Detroit Free Press reports.

While his long-term future in Detroit remains murky, Skubal will once again head into the 2026 campaign as the staff ace coming off back-to-back AL Cy Young Awards. The Tigers may look to manage Skubal's innings during the Grapefruit League after he logged a combined 216 frames between the regular season and playoffs in 2025, but he should be fully ramped up and ready to handle a standard workload by the time Opening Day arrives.

Hader will resume a throwing program Wednesday after being shut down since early February with left bicep inflammation, Chandler Rome of the Houston Chronicle reports.

It seems the left shoulder strain that sidelined Hader for the final seven-plus weeks of last season is behind him, but now he has a new injury to contend with. The veteran reliever will resume throwing Wednesday and ramp up slowly, and his status for Opening Day is up in the air. If Hader needs some time on the injured list, Bryan Abreu would step in as the Astros' closer.

The Tigers announced Wednesday that Darnell (hip) will be sidelined for the start of spring training, Chris McCosky of The Detroit News reports.

Darnell is still on the mend from left hip labral repair surgery, which he underwent last September. Before being shut down by the injury, the 28-year-old righty made nine appearances out of the Colorado bullpen and logged a 3.86 ERA, 1.46 WHIP and 5:7 K:BB across 11.2 innings. After being claimed off waivers by the Tigers in November, Darnell was designated for assignment but then re-signed to a minor-league deal. He's attending camp as a non-roster invitee, but he'll likely need to complete his rehab within the next week or two to have any shot at all of winning a spot in the Opening Day bullpen.