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Three weeks of the 2024 NFL schedule are now in the books, and Fantasy football injuries are starting to pile up. At the wide receiver position, Puka Nacua (knee), A.J. Brown (hamstring), and Cooper Kupp (ankle) all missed Week 3, and are unlikely to play in Week 4. Running backs Christian McCaffrey (calf), Austin Ekeler (concussion), Alvin Kamara (ribs), and Joe Mixon (ankle) are all banged up as well. If you have those players in your fantasy football lineups, finding the top values and making the right fantasy football waiver wire claims could be the key to salvaging your season.

How would the Week 4 fantasy football wide receiver rankings look without Nacua, Brown, and Kupp in the mix? Are there any fantasy football sleepers worth targeting on the waiver wire? Before you lock in your lineups, be sure to check out the Week 4 Fantasy football rankings from the proven computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons, especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty-handed.

The same model has a proven track record of providing Fantasy football tips, including being ahead of the curve on players like A.J. Brown, Jonathan Taylor, Derrick Henry, Christian McCaffrey, Alvin Kamara, and Jahmyr Gibbs. Anybody who banked on players like those made a run at their league title.

Now, SportsLine has simulated the entire Week 4 NFL schedule 10,000 times and released its latest Week 4 Fantasy football rankings. Head to SportsLine now to see them

Top Week 4 Fantasy football QB rankings

Here's a look at SportsLine's top Week 4 Fantasy football QB picks: 

1. Kyler Murray, Arizona Cardinals: When healthy, Murray has been one of the most productive fantasy quarterbacks in the NFL. His dual threat ability is great from a fantasy perspective, and the former Oklahoma standout has been efficient through the air this season, throwing for 635 yards and five touchdowns through three games. Murray will face a Washington Commanders defense that ranks 29th in the NFL, allowing 377.3 yards per game.

2. Jayden Daniels, Washington Commanders: Daniels has emerged as the favorite to win NFL Offensive Rookie of the Year in 2024. The reigning Heisman Trophy winner has completed 80.3% of his passes for 664 yards and two touchdowns, and he's rushed for 171 yards and three scores. His ability as a runner makes him a high-end fantasy quarterback option heading into Week 4.

3. Joe Burrow, Cincinnati Bengals: The Bengals came up short in Week 3, but Burrow had his best game of the season, throwing for 324 yards and three touchdowns. The former LSU star has the benefit of having two elite wide receivers at his disposal (Ja'Marr Chase and Tee Higgins), and he will be facing the league-worst Carolina Panthers defense in Week 4. See more top QBs here.

Top Week 4 Fantasy football RB rankings

Here's a look at SportsLine's top Week 4 Fantasy football RB picks: 

1. De'Von Achane, Miami Dolphins: After back-to-back games with 100-plus scrimmage yards in each of his first two weeks, Achane was held in check by Seattle's No. 4 scoring defense. However, he'll face the Titans on MNF, and Tennessee ranks 24th in defense and has allowed four touchdowns to running backs over the last two weeks alone.

2. Breece Hall, New York Jets: With 20-plus touches and a touchdown in every game so far, Hall is as consistent as they come. He'll now get to face the Broncos, who Hall torched for 194 scrimmage yards and a touchdown in Week 5 of last season.

3. Saquon Barkley, Philadelphia Eagles: Leading the NFL in touchdowns (five), rushing yards (351) and touches (73), Barkley may be the early-season frontrunner to win Offensive Player of the Year. His receiving chops should come in handy against Tampa, which has allowed both the most catches and receiving yards to RBs in 2024. See more top RBs here.

Top Week 4 Fantasy football WR rankings

Here's a look at SportsLine's top Week 4 Fantasy football WR picks: 

1. Nico Collins, Houston Texans: The fourth-year pro enters Week 4 leading the NFL in receiving yards (338), and he has a great chance of expanding his lead against the Jags. Collins had a 7-104-1 stat line in his last game versus Jacksonville, and the Jaguars have allowed the sixth-most receptions and receiving yards to WRs in 2024.

2. Marvin Harrison Jr., Arizona Cardinals: After a quiet Week 1, the real Harrison has emerged over the last two games with 194 yards and three TDs over that span. Now, he gets the tastiest matchup of his young career in facing a Washington defense on Sunday which has allowed the most Fantasy points to opposing wideouts.

3. Justin Jefferson, Minnesota Vikings: Jefferson leads the NFL in receiving TDs (three) and has recorded one in each week. He's already developed great chemistry with QB Sam Darnold, and Jefferson has averaged 97 receiving ypg over his last five contests with the Packers. See more top WRs here.

Top Week 4 Fantasy football TE rankings

Here's a look at SportsLine's top Week 4 Fantasy football TE picks:

1. Trey McBride, Arizona Cardinals: McBride has yet to find the end zone, but he remains one of Kyler Murray's favorite targets. He had a 28.8% target share through two weeks and will now get a favorable matchup against the Commanders on Sunday. 

2. Dallas Goedert, Philadelphia Eagles: Goedert was extremely effective in Philadelphia's victory over the Saints on Sunday, bringing in 10 of 11 targets for 170 yards. Both Goedert's reception and receiving yardage totals were career highs, and he could be in line for another busy outing when the Eagles take on the Tampa Bay Buccaneers on Sunday. 

3. Travis Kelce, Kansas City Chiefs: Kansas City's star tight end has a meager 69 receiving yards and has yet to score a touchdown heading into a Week 4 road game against the Chargers. However, Kelce remains a scoring threat in the red zone and one of Patrick Mahomes' favorite targets in the passing game. See more top TEs here.

Top Week 4 Fantasy football defense rankings 

Here's a look at SportsLine's top three Week 4 Fantasy football D/ST picks:

1. Jets D/ST: The Jets are extremely stingy against the pass, ranking fourth in the NFL in passing yards allowed per game (150.7). The Jets held the Patriots to just three points in their only home game this season and on Sunday, New York hosts the Denver Broncos, an offense that has six turnovers this season. 

2. Packers D/ST: Green Bay's defense dominated in last week's victory over the Titans, recording eight sacks and two interceptions. 

3. Dolphins D/ST: The Dolphins are giving up 294.7 yards per game this season, which ranks 11th in the NFL. Miami will now face a Titans team that leads the NFL with eight turnovers on offense. Tennessee also gave up eight sacks last week against the Packers. See more top D/ST here

How to get Week 4 Fantasy football rankings

Now that you know who the top three at each position are, you'll want to see the full Week 4 Fantasy football rankings from SportsLine. The model has identified a stunner in the top 10 at running back, and knowing who it is can give you a huge edge in your league. Head to SportsLine now to get Week 4 Fantasy football rankings

So who should you target in your Week 4 Fantasy football rankings, and which surprising RB could lead you to victory? Visit SportsLine now to get Week 4 Fantasy Football rankings for every single position, all from the model that has a history of making league-winning calls, and find out.