Player News

• 49ers' Isaac Guerendo: Role remains marginalized

  6D ago • By RotoWire

  Guerendo logged three snaps on special teams in Sunday's 37-24 win over the Titans. Guerendo remained a non-factor on offense behind Christian McCaffrey and Brian Robinson on San Francisco's running back depth chart. The 25-year-old Guerendo once returned kickoffs for the 49ers, but the team has removed him from that role completely since Week 5. Barring a string of catastrophic injuries in the backfield, Guerendo can safely be ignored during the fantasy playoffs.

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• 49ers' Isaac Guerendo: No run on offense this season

  10/29/2025 • By RotoWire

  Guerendo played all 10 of his snaps on special teams in Sunday's 26-15 loss to the Texans. As a rookie last season, Guerendo showcased some explosiveness out of the San Francisco backfield with averages of 5.0 yards per carry and 10.1 yards per reception over 16 games, but he has yet to play a snap on offense in the 49ers' first eight games of 2025. With lead back Christian McCaffrey having thus far stayed healthy while handling huge snap and touch counts each week, Brian Robinson has picked up the remaining scraps left over in the backfield. So long as McCaffrey and Robinson are able to avoid injury, Guerendo looks as though he'll be limited to a role on kickoff returns and kick-coverage units.

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• 49ers' Isaac Guerendo: Returns one kickoff Thursday

  10/03/2025 • By RotoWire

  Guerendo ran back one kickoff for 18 yards while receiving no carries or targets in Thursday's 26-23 overtime win over the Rams. Christian McCaffrey continued to operate as San Francisco's bell cow (88 percent) while Brian Robinson (14 percent) remained the clear No. 2, which leaves Guerendo parked in the garage when the team is on offense. The 2024 fourth-round selection is stuck on special teams for the foreseeable future, needing an injury ahead of him on the depth chart to open up playing time. Guerendo generates no fantasy value in his current role when the 49ers visit the Buccaneers in Week 6.

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• 49ers' Isaac Guerendo: Full practice Wednesday

  09/03/2025 • By RotoWire

  Guerendo (shoulder) practiced fully Wednesday, Cam Inman of The San Jose Mercury News reports. Guerendo exited practice on Aug. 2 due to a shoulder injury and sat out the next two-and-a-half weeks, only to be healthy enough to play in the 49ers' preseason finale Aug. 23 and turn eight carries into 13 yards and one catch (on one target) into one yard. In the midst of it all, the team traded for Commanders RB Brian Robinson, placing Guerendo's status into question heading into Week 1. Even though Guerendo has a clean bill of health in advance of Sunday's contest at Seattle, he may play third fiddle out of San Francisco's backfield to starter Christian McCaffrey and Robinson.

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• 49ers' Isaac Guerendo: Facing competition from Robinson

  08/22/2025 • By RotoWire

  Guerendo may open the season as San Francisco's No. 2 running back even though the team is trading for Brian Robinson, Cam Inman of The San Jose Mercury News reports. The 49ers presumably wouldn't trade for Robinson, even at the cost of just a sixth-round pick, unless they thought he could become their No. 2 running back. That doesn't mean he'll simply be handed the gig, however, nor does it mean he'll be comfortable with the playbook in time for Week 1 at Seattle. Still, the trade takes a chunk out of Guerendo's fantasy value, adding another legitimate competitor for backup roles after the Niners drafted Jordan James (finger) in the fifth round this spring. Guerendo is the fastest and most athletic of the bunch, but his injury history dating back to college is concerning, to say the least.

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