NFL Player News

Mayfield headed to the locker room late in the second quarter of Sunday's game against the Steelers with an apparent hand injury, Tom Reed of The Athletic reports.

Mayfield appeared to hit his hand or thumb on a helmet, per Pat McManamon of The Athletic, which led to the QB's exit from the contest. As a result, Garrett Gilbert finished up the second quarter in place of Mayfield.

Murray (hamstring) is active for Sunday's game versus the Rams, Darren Urban of the Cardinals' official site reports.

Murray made an appearance on the Cardinals' injury report Friday as a full participant but nonetheless was listed as questionable for Week 13 due to a hamstring issue. The team revealed its hand Saturday when it didn't stop the Lions from plucking QB Kyle Sloter from the practice squad. Still, Murray's availability came down to the release of inactives Sunday afternoon. He'll aim to produce against a Rams defense that has given up 248.6 yards per game and an 18:7 TD:INT to quarterbacks in 11 contests this season.

Drew Lock will start Sunday against the Chargers with Allen moving to a backup role, Adam Schefter of ESPN reports.

Allen's putrid outing in the Week 12 loss at Buffalo led the Broncos to turn to Lock, who came off injured reserve after missing 12 games with a thumb injury. Allen may serve as the backup the rest of the season.

Lock will start Sunday against the Chargers, Adam Schefter of ESPN reports.

The rookie took first-string reps at practice throughout the week, so Denver will give him a look with Brandon Allen as his backup. Lock was activated from injured reserve this week after missing the first 12 weeks with a sprained thumb in his throwing hand.

Murray (hamstring), who is listed as questionable on the official injury report, will start Sunday against the Rams, a source told Adam Schefter of ESPN.

Murray was able to practice fully Friday despite garnering a questionable tag, so his availability for Week 13 makes sense. Still, fantasy managers will want to check his status before the 4:05 p.m. ET kickoff.

Rypien was waived by the Broncos on Saturday, Mike Klis of 9News Denver reports.

The Broncos activated Drew Lock (thumb) on Saturday so it shouldn't come as much of a surprise to see the team waive its backup signal caller. It's entirely possible Rypien could return to the team's practice squad after a near month-long stint on the 53-man roster.

Blough is expected to remain the starter until the return of Matthew Stafford (back) after backup Jeff Driskel (hamstring) was placed on injured reserve Saturday, Ian Rapoport of NFL Network reports.

Blough was surprisingly stout in his professional debut Thursday, carving through the Bears' defense and keeping the contest close throughout. The 24-year-old looks to be in line for more starts along the way, as Matthew Stafford doesn't seem close to a return (back) and former backup Jeff Driskel is on injured reserve, so Blough should be in line to take on the Vikings in Week 14.

Driskel (hamstring) was placed on injured reserve Saturday, Ian Rapoport of NFL Network reports.

While Driskel was technically active for Thursday's Thanksgiving Day loss to the Bears, it certainly didn't seem as if the backup quarterback was healthy enough to compete, so Saturday's roster designation shouldn't come as much of a surprise. The Lions have not placed Matthew Stafford on injured reserve despite multiple fractures in his back, but considering their dismal record it's entirely possible the team decides to play it incredibly cautious with its franchise signal caller. David Blough, the team's third-string option and Thursday's starter, looked solid in his professional debut and figures to continue reprising the role until Stafford is deemed healthy enough to compete, though Detroit did sign Kyle Sloter as an insurance policy off the Cardinals' practice squad.

Lock (thumb) has officially been activated off injured reserve ahead of Sunday's game against the Chargers, but it remains unclear who will start under center between him and Brandon Allen, Mike Klis of 9News Denver reports.

Although no official starting quarterback has been announced, Lock is considered the favorite to get the opportunity. The rookie took first-string reps at practice throughout the week, which indicates the Broncos are going to see what they have in their second-round pick. Both Joe Flacco (neck) and Allen struggled to get the offense moving this year, so we may have an opportunity to see if Lock has the key to jump-start it.

Murray was added to Friday's injury report with a hamstring issue, Mike Jurecki of the Cardinals' official site report. He's listed as questionable for Sunday's game against the Rams.

Murray's ability to maintain full practice participation Friday suggests the injury isn't too serious, but the timing nonetheless creates some concern. A 4:05 p.m. ET kickoff is suboptimal for fantasy managers, limiting the available alternatives if Murray does end up as a game-time decision. Brett Hundley is the backup quarterback in Arizona.