Stafford completed 22 of 31 pass attempts for 281 yards and three touchdowns in Sunday's 45-17 rout of the Cardinals.

Stafford wasted no time getting back to his MVP-bid form after uncharacteristically committing three turnovers in last week's surprising loss to Carolina. The 37-year-old extended his streak of throwing multiple touchdown passes to seven games while making an example of Arizona's secondary. With 35 touchdowns thrown through 13 weeks, Stafford has nearly built a double-digit margin between himself and Dak Prescott/Jared Goff (26) for the league lead in the category. The fantasy star is already producing at a high level as the playoff schedule approaches, but Stafford may find added motivation playing against the club that drafted him in 2009 when the Rams host the Lions next Sunday.

Lawrence completed 17 of 30 passes for 244 yards, two touchdowns and no interceptions in Sunday's 36-19 win over the Colts. He added 16 yards on four carries.

The Jaguars had a relatively easy win after Daniel Jones (Achilles) exited Sunday's game, but Lawrence managed to get his numbers early. He completed four passes of at least 25 yards, three of which came in the first two quarters, while also tallying touchdown throws of 14 and seven yards. While he attempted only 10 passes in the second half, Lawrence managed his third consecutive multi-score game while also reaching at least 225 passing yards for the third consecutive contest.

Pickett completed eight of 11 passes for 97 yards, one touchdown and no interceptions in Sunday's 24-17 loss to the Broncos. He added one rush for six yards.

Pickett played the entire fourth quarter in relief of Geno Smith, who exited with a shoulder injury. The former led two garbage-time drives with the Raiders down three and two scores, respectively, showing good rapport with Jack Bech while also hitting Shedrick Jackson for a 25-yard score. This was Pickett's third appearance of the season, by far his most prolonged, and he could be in line to start in Week 15 against the Eagles pending the severity of Smith's injury.

Nix completed 31 of 38 pass attempts for 212 yards while adding three carries for 15 yards and a touchdown in Sunday's 24-17 win against Las Vegas.

Nix was methodical against the Raiders' coverage Sunday, completing over 80 percent of his pass attempts en route to earning his team's 11th victory of the season. The Broncos played an excellent game of ball control, nearly doubling the opposition's 20:57 time of possession. This was exhibited best on Denver's opening drive that ate up just under nine minutes of game clock, which culminated in Nix's fourth rushing touchdown of the season, tying the mark he set last year as a rookie. The Broncos' special teams and running game finished off the Raiders, which helped contribute to the signal-caller's pedestrian individual contribution to fantasy managers' box scores in Week 14. Nix will face a stiffer test next time out when the Broncos host the Packers next Sunday.

Shough completed 13 of 20 passes for 144 yards with no touchdowns and one interception while adding seven rushes for 55 yards and two touchdowns in the Saints' 24-20 win over the Buccaneers on Sunday.

Shough took three sacks and generated the third sub-200-yard tally through the air of his six-game starting tenure, but the rookie signal-caller shined with his work on the ground. Shough recorded the first two rushing scores of his career on 34- and 13-yard runs, the latter play coming with 8:26 remaining in the game and snapping a 17-17 tie. Shough also established a new career high in rushing yardage in the upset victory, and his penchant for keeping the Saints competitive most weeks affords him a reasonably optimistic outlook for a Week 15 home divisional clash against the Panthers.

Mayfield completed 14 of 30 passes for 122 yards with a touchdown and an interception while adding six rushes for 42 yards in the Buccaneers' 24-20 loss to the Saints on Sunday.

Mayfield's final line underscores the type of afternoon it was for the normally efficient veteran signal-caller, who surprisingly struggled to a 44.9 QBR in a game for which the Buccaneers were heavily favored. Mayfield connected with Bucky Irving for a 24-yard touchdown pass just before the midway point of the first quarter, but his one interception on a deep pass to Kameron Johnson early in the third quarter led to a Saints touchdown. Mayfield could get Mike Evans (IR, collarbone) back for a Week 15 home matchup against the Falcons on Thursday night to help the quarterback bounce back from his lowest passing yardage total in a non-injury-shortened game this season.

Smith exited Sunday's game against the Broncos after sustaining a right hand injury.

With Smith headed to the locker room, per Mike Garafolo of NFL Network, Kenny Pickett is in at QB for the Raiders. Aidan O'Connell was designated the team's emergency No 3 QB on Sunday. Prior to his departure, Smith completed 13 of his 21 pass attempts for 116 yards and a TD and carried once for four yards.

Allen completed 22 of 28 passes for 251 yards and three touchdowns in Sunday's 39-34 win over the Bengals. He added 78 rushing yards and a TD on nine carries.

The Bills found themselves staring at a 21-11 deficit at halftime, but Allen once again put the team on his back in a comeback victory, with a 40-yard touchdown run in the snow midway through the fourth quarter being his biggest play -- the longest regular-season TD run in history by a Buffalo quarterback, breaking his own record. Allen has reached 12 rushing touchdowns for the third straight season while also producing a 22:10 TD:INT in 13 games, and he'll likely need to be sharp again in a huge AFC East showdown against the Patriots in Week 15.

Leonard completed 18 of 29 passes for 145 yards for no touchdowns and one interception in Sunday's 36-19 loss to the Jaguars. He added two rushes for five yards and a rushing touchdown.

Leonard entered the game late in the first quarter after Daniel Jones suffered an Achilles injury. It was Leonard's second appearance as a pro, and some inconsistencies followed, as expected. Positively, he used his mobility well to extend plays, on one occasion hitting Alec Pierce on the run for a 24-yard gain. Leonard also scrambled for a touchdown late in the fourth quarter to record his first NFL score. On the other hand, he had a pass intercepted and was also sacked for a safety on back-to-back possessions in the fourth quarter to put the game out of reach for the Colts. Jones' injury is feared to be season-ending, lining Leonard up to be the starter so long as Anthony Richardson (eye) is also out.

Sanders completed 23 of 42 passes for 364 yards with three touchdowns and one interception while adding three rushes for 29 yards and another score in the Browns' 31-29 loss to the Titans on Sunday.

Sanders' final line emphasizes the breakout quality of the rookie's performance, which was fueled by a 60-yard touchdown pass to Jerry Jeudy, another pair of passing scores to David Njoku (one yard) and Harold Fannin (seven yards), and a seven-yard rush TD, with the latter two plays occurring in the fourth quarter. Head coach Kevin Stefanski opted to take the ball out of Sanders' hands during an attempt at a game-tying two-point conversion after the touchdown pass to Fannin, but it was otherwise another significant step in the right direction for the fifth-round pick. Sanders showed increasing command of the offense by spreading the ball around to eight different targets, and he'll next make a trip to Soldier Field to face off with the Bears next Sunday.