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Darrel Williams RB | NO
Chiefs' Darrel Williams: Totals 110 yards
Williams rushed 13 times for 49 yards and caught all six of his targets for 61 yards in Monday night's 20-17 win over the Giants.
Williams saw backup Derrick Gore enjoy a first-half outburst that enabled him to finish with 11 carries for 48 yards and a touchdown, but the veteran gained stream during the second half. With a combination of handoffs and check-down receptions, Williams ultimately posted 110 yards from scrimmage, his most of this season. With it currently unknown whether usual starter Clyde Edwards-Helaire (knee) is expected to return in Week 9 versus the Packers, the outlooks of Williams, Gore and Jerick McKinnon could be dependent on Edwards-Helaire's status as the week unfolds, making Kansas City's backfield situation worth monitoring in the coming days.
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Larry Rountree III RB | HOU
Chargers' Larry Rountree: Four carries in loss
Rountree carried the ball four times for 11 yards in Sunday's 27-24 loss to the Patriots.
The Chargers ran just 18 designed runs on an afternoon in which the Patriots sat on the ball with a successful rushing attack. One game after serving as a healthy inactive, Rountree at least managed to pick up a handful of carries, but he hardly did anything with the opportunities. Primarily a short-yardage ballcarrier, Rountree is averaging a pitiful 2.5 yards-per-carry through 28 attempts this season.
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Trayveon Williams RB | DET
Trayveon Williams: Reverts to practice squad
Williams reverted to the Bengals' practice squad Monday, per the NFL's official transaction log.
Williams was called up to add depth to Cincinnati's running back group with Chris Evans (hamstring) unable to go Sunday against the Jets. Williams ultimately only played eight snaps, all on special teams. If Evans misses Week 9 against the Browns, Williams will look for another chance to play Sunday.
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Saquon Barkley RB | PHI
Giants' Saquon Barkley: Aiming for Week 9 return
Barkley told Lisa Salters of ESPN that he didn't play Monday at Kansas City due to "too much swelling and soreness" in his left ankle, but he hopes to be available Sunday against the Raiders.
The Giants have a Week 10 bye, so they could proceed with caution and hold Barkley out for a fourth straight game in Week 9, but the running back appears to be seeking some game action before the team's midseason respite. Prior to spraining his ankle back in Week 5, he averaged 16.5 touches for 79 yards from scrimmage per game and scored three TDs through the first four contests of the campaign. While Barkley goes through the final stages of his recovery, the Giants will continue to go with Devontae Booker and fullback Elijhaa Penny out of the backfield.
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Jeff Wilson RB | MIA
49ers' Jeff Wilson: Returning to practice soon
The 49ers are expected to open the practice window for Wilson (knee) this week, Matt Maiocco of NBC Sports Bay Area reports.
Wilson has resided on the PUP list since the start of training camp due to May surgery to repair a torn meniscus. Such a listing required him to spend at least the first six contests of the season on the sideline, but he wasn't expected to be ready for game action until midseason in any case. If the 49ers designate Wilson to return in the coming days, he'll have a three-week window in which to prove the health of his knee. The team is down Raheem Mostert for the season with chipped cartilage in his left knee, leaving Elijah Mitchell (ribs), JaMycal Hasty, Trey Sermon and Trenton Cannon as the running backs on San Francisco's active roster.
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Elijah Mitchell RB | PHI
49ers' Elijah Mitchell: Tending to rib injury
Mitchell is dealing with a rib injury and is expected to be limited in practice Wednesday, Nick Wagoner of ESPN.com reports.
Mitchell ran roughshod over the Bears on Sunday, turning 18 carries into 137 yards and one touchdown. It marked his third 100-yard game in five appearances as a pro, but he's also now poised to appear on the 49ers' injury report for the second time this season. With practice limitations set to be placed on Mitchell, the team's healthy running backs are JaMycal Hasty, Trey Sermon and Trenton Cannon, while Jeff Wilson's (knee) practice window to return from the PUP list may open this week and Raheem Mostert (knee) is out for the season.
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Alexander Mattison RB | MIA
Vikings' Alexander Mattison: Just four touches Sunday
Mattison had two carries for five yards and lost five yards on two receptions in Sunday's 20-16 loss to Dallas.
Mattison played eight snaps on offense as he had a minimal role with Dalvin Cook fully healthy. Mattison eclipsed 100 rushing yards in both spot starts when Cook has sat out this season, so he's one of the more valuable backups in the league. However, Mattison likely will have minimal fantasy value most games when Cook is healthy.
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Derrick Henry RB | BAL
Titans' Derrick Henry: Officially on IR
Henry (foot) has been placed on IR by the Titans, Jim Wyatt of the team's official site reports.
This was an expected move, with Wyatt having previously noted that the running back is slated to undergo foot surgery Tuesday. Though coach Mike Vrabel didn't offer a timetable for Henry's recovery, Ian Rapoport of NFL Network has suggested that Henry is expected to miss 6-10 weeks. In the meantime, Jeremy McNichols, Dontrell Hilliard and practice-squad member Mekhi Sargent are internal options to see added backfield work, while veteran RB Adrian Peterson reportedly is in line to be added to Tennessee's practice squad, with the expectation he'll be promoted to the team's active roster.
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Nyheim Miller-Hines RB | NO
Colts' Nyheim Hines: Four receptions Sunday
Hines had one carry for two yards and four receptions for 22 yards on five targets in Sunday's 34-31 overtime loss to Tennessee.
Hines played on 25 of the offense's 80 snaps despite being limited in practice last week due to a rib injury. He was tied for third on the team in targets, but continues to have a limited role in the offense, as he hasn't had a game with more than 10 touches since Week 3.