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Raheem Mostert RB | LV
49ers' Raheem Mostert: Could play Sunday
Mostert (ankle) will be activated from injured reserve before Sunday's game against the Rams, with coach Kyle Shanahan considering the running back questionable to play, Nick Wagoner of ESPN.com reports.
Jeff Wilson (IR - ankle) will get the same treatment, while Tevin Coleman (knee) has been ruled out. Mostert should be the lead back if he ends up playing, but the 49ers also have Jerick McKinnon on hand, and it sounds like Wilson has a shot as well. It could come down to a game-time decision for Mostert and/or Wilson.
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Corey Clement RB | ARI
Eagles' Corey Clement: Lifted from COVID list
The Eagles activated Clement from the reserve/COVID-19 list Friday, Daniel Gallen of The Harrisburg Patriot-News reports.
Clement was a high-risk close contact when he was placed on the list. The 26-year-old running back will be available for Monday's game against the Seahawks. The Wisconsin product isn't expected to play much if Boston Scott (abdomen) is active.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Good to go
Kamara (foot) doesn't have an injury designation for Sunday's game in Denver.
The Saints have limited Kamara's practice workloads while he deals with a foot injury, but there was never any question he'd be ready for Sunday. He had his worst fantasy performance of the season in Taysom Hill's first start at quarterback, but Kamara did still score a touchdown to avoid a total dud.
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Gus Edwards RB | LAC
Ravens' Gus Edwards: Ravens-Steelers moved to Tuesday
Edwards and the Ravens won't play Sunday at Pittsburgh after the NFL announced the game was rescheduled for Tuesday, Adam Schefter of ESPN reports.
Even with this game getting moved for a second time, Edwards is poised to lead Baltimore's backfield after both Mark Ingram and J.K. Dobbins tested positive for COVID-19 on Monday. Considering the Ravens rank second in the NFL in rush play percentage (51.9) and Edwards has averaged 5.1 yards per carry through two-plus seasons, he could have a productive outing Tuesday, assuming the game is played.
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Austin Ekeler RB | WAS
Chargers' Austin Ekeler: May return Sunday
Coach Anthony Lynn said Ekeler (hamstring) has "a chance" to be activated from injured reserve before Sunday's game at Buffalo, Daniel Popper of The Athletic reports.
The Chargers opened Ekeler's 21-day practice window this week, indicating he was close to completing his recovery from a left hamstring injury suffered Week 4. He's missed six games as a result, and the team will need to make a decision on whether or not he'll miss a seventh by Saturday afternoon. Even if he's able to play Sunday, it'll be interesting to see the breakdown of reps out of the backfield. Kalen Ballage (ankle) is questionable for the contest, so Ekeler has a chance to retake the No. 1 role right away if L.A. deems him to be ready for such a workload.
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Myles Gaskin RB | SEA
Dolphins' Myles Gaskin: Could be activated this week
Coach Brian Flores relayed Friday that the team's coaching staff will review the film on Gaskin (knee) before determining if he'll be activated for Sunday's game against the Jets, Cameron Wolfe of ESPN.com reports.
Gaskin, who is still on IR, has been practicing this week and if he is indeed deemed fit to play this weekend, there's a path for him to reclaim the team's lead role, with Salvon Ahmed (shoulder) having been ruled out for Sunday's contest. Miami's other backfield options include Matt Breida, Patrick Laird and DeAndre Washington.
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Salvon Ahmed RB | CHI
Dolphins' Salvon Ahmed: Won't play Sunday
Ahmed (shoulder) won't play Sunday against the Jets, Armando Salguero of the Miami Herald reports.
Though Ahmed is out this week, the Dolphins have the option of activating Myles Gaskin (knee) from IR in advance of Sunday's game. Per Cameron Wolfe of ESPN.com, Brian Flores relayed that the team plans to review the practice film on Gaskin before determining his Week 12 status. Miami's other backfield options include Matt Breida, Patrick Laird and DeAndre Washington.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: Officially listed as questionable
McCaffrey (shoulder) is listed as questionable for Sunday's game in Minnesota, though he doesn't seem likely to play, Bill Voth of the Panthers' official site reports.
"I'm pessimistic that he'll play," said Panthers coach Matt Rhule after Friday's practice. "But he's done enough this week to earn the right to have a chance." In any case, while McCaffrey's coach apparently doesn't expect him to play, it's interesting that the Panthers opted for 'questionable' rather than 'doubtful as the official designation. The star running back was a limited practice participant throughout the week, and he's expected to travel to Minnesota with his teammates, David Newton of ESPN.com reports.
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Tony Pollard RB | TEN
Cowboys' Tony Pollard: Little usage in Thanksgiving loss
Pollard carried the ball four times for 12 yards and caught both his targets for 10 yards in Thursday's loss to Washington.
Despite another fumble from Ezekiel Elliott, Pollard didn't see much action in the Thanksgiving Day rout, continuing a trend from last week -- after getting at least eight touches in five straight games prior to the Cowboys' bye, Pollard has only 11 touches total in the last two contests. As long as Dallas has a shot at winning their division, Elliot's workload isn't likely to decline, leaving Pollard's usage dependent on game flow rather than his abilities.
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Scottie Phillips RB | HOU
Texans' Scottie Phillips: Small role in win
Phillips played four offensive snaps and did not get a touch in Thursday's 41-25 win over the Lions.
Phillips was added to the active roster, giving the Texans another skill player with wide receivers Randall Cobb (toe, IR) and Kenny Stills (quadriceps) unavailable. He was primarily used on special teams. With running back David Johnson (concussion) eligible to return Week 13 against Indianapolis, Phillips' spot on the roster hinges on the status of Johnson and the wideouts.