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Miles Sanders RB | DAL
Eagles' Miles Sanders: Leads backfield
Sanders rushed the ball 12 times for 63 yards in the team's Week 12 loss to the Seahawks. He also added three receptions on five targets for 23 yards.
Sanders tallied 15 total touches, matching the highest mark of his rookie campaign. He was largely bottled up on the ground in the first half, but he managed more than five yards on seven of his carries overall. Sanders also contributed in the passing game, and he has now recorded at least three receptions in five of his last six contests. While Sanders appears to be gaining a foothold in the offense, Jordan Howard (shoulder) may be ready to return in Week 13 as the Eagles take on the Dolphins, complicating the touch distribution in the backfield once again.
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Saquon Barkley RB | PHI
Giants' Saquon Barkley: Limited in loss
Barkley rushed 17 times for 59 yards and caught two of three targets for one yard in Sunday's 19-14 loss to the Bears.
Chicago's defense did a good job of limiting Barkley, especially as a receiver out of the backfield, as he set season lows in both catches and receiving yards. Barkley has been mostly a decoy in the red zone, as he remains stuck on just two rushing touchdowns and one receiving score this season. He's also failed to eclipse 100 yards on the ground since doing so in each of the season's first two games. Barkley will hope to get back on track when the Packers come to town in Week 13.
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Benny Snell RB | DET
Steelers' Benny Snell: Heads backfield vs. Bengals
Snell carried 21 times for 98 yards and added a five-yard catch during Sunday's 16-10 win over the Bengals.
Snell returned from a knee injury and showed no lingering effects, as he topped 20 carries for the first time in his NFL career. He averaged 4.7 yards per tote against a beatable Cincinnati defense and topped 100 scrimmage yards for the first time as well. Snell appears to be the go-to ball carrier with James Conner (shoulder) sidelined, and he will look to build on this breakout effort next Sunday against the Browns.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: Another fantasy gem
McCaffrey rushed 22 times for 64 yards and a touchdown while catching all nine of his targets for 69 yards and a touchdown in Sunday's 34-31 loss to the Saints.
McCaffrey had a one-yard touchdown among his nine catches, and he later added a four-yard score on the ground. The multi-faceted running back now has 12 rushing scores and four more through the air, and McCaffrey has caught the ball 20 times in his last two games alone. Even when he doesn't do much on a per-touch basis, McCaffrey's nose for the end zone and heavy volume week in and week out make him arguably the most valuable asset in the fantasy realm.
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Devin Singletary RB | NYG
Bills' Devin Singletary: Tallies 114 yards in win
Singletary ran for 106 yards on 21 carries and added an eight-yard catch during Sunday's 20-3 win over Denver.
The Broncos came into Sunday as one of the stingier run defenses in the league over the past month or so, but Singletary plugged away for his first career 100-yard rushing performance. The rookie has been magnificent moving the chains this season, averaging 5.9 yards per carry despite just five carries of over 20 yards and none of 25 or more yards this season. His role is continuing to increase, with at least 16 touches in three of his last four games, and he should be counted on Thursday against a Dallas defense that is ranked in the top 10 in the league against the pass but one that has been a little more generous against the run this season.
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Ronald Jones RB | DAL
Buccaneers' Ronald Jones: Bulls his way to TD in win
Jones rushed 12 times for 51 yards and a touchdown and secured all three targets for 16 yards in the Buccaneers' 35-22 win over the Falcons on Sunday.
Jones split run-game work almost evenly with Peyton Barber, who logged 11 carries himself. However, it was Jones who got a touchdown opportunity and made good with it, powering his way into the end zone from four yards out to cap off the opening drive of the second half for the Buccaneers. The score was Jones' fifth of the season, all of which have come on the ground. The second-year back will look to follow up his solid performance when he faces the vulnerable Jaguars run defense Week 13.
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Nick Chubb RB | HOU
Browns' Nick Chubb: Scores with 164 scrimmage yards
Chubb carried 21 times for 106 yards during Sunday's 41-24 win over the Dolphins. He also caught three of four targets for 58 additional yards.
Chubb exploited this favorable matchup to the tune of 5.0 yards per carry, as he topped the 100-yard mark for the fifth time this season. He also notched a new season high in receiving yardage thanks to a couple of big plays in the passing game. Kareem Hunt scored a short rushing touchdown in the first half, but Chubb got one of his own in the final minutes to end a four-game run without a TD. The second-year back continues to produce at a strong rate and will look to do so again next Sunday against the Steelers.
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Rashaad Penny RB | CAR
Seahawks' Rashaad Penny: Erupts for 129 yards, touchdown
Penny rushed 14 times for 129 yards and a touchdown in Sunday's 17-9 win over the Eagles.
Penny entered the contest with just 167 rushing yards as the secondary option to Chris Carson, but the second-year pro out-touched Carson 14-12 and outgained him by 72 yards. His day was highlighted by breaking free for a career-best 58-yard touchdown run in the fourth quarter, as he showcased the explosiveness that enticed the Seahawks to select him in the first round of the 2018 NFL Draft. Coach Pete Carroll stuck with the hot hand in this low-scoring affair, and Penny likely earned additional looks going forward. The Seahawks host Minnesota in Week 12.
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Josh Jacobs RB | GB
Raiders' Josh Jacobs: Lays egg against Jets
Jacobs rushed 10 times for 34 yards and caught his lone target for two yards in Sunday's 34-3 loss to the Jets.
Jacobs and starting quarterback Derek Carr were both taken out of the game late in the third quarter with the Raiders trailing 34-3. The rookie running back still is locked in as Oakland's workhorse on the ground, but nothing went right for his team in this one. He'll have an opportunity to bounce back against the vulnerable Chiefs run defense Week 13, in a game the Raiders will need to win to keep pace in the AFC West.
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Damien Harris RB | BUF
Patriots' Damien Harris: Sitting out Sunday
Harris (hamstring) is inactive for Sunday's game against the Cowboys.
Harris was limited at practice all week, and he'll sit out a fourth straight game, although only two were attributed to this injury. The Patriots' backfield remains deep with Sony Michel, James White, Rex Burkhead and Brandon Bolden.