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Marlon Mack RB | ARI
Colts' Marlon Mack: Week 13 status uncertain
Mack (concussion) may not be available to play in Sunday's game against the Jaguars, Mike Chappell of Fox 59 News Indianapolis reports.
Mack suffered the concussion in the fourth quarter of the Colts' 27-24 win over Miami in Week 12, finishing with 85 yards on 15 carries and 11 yards on two receptions. His status for Sunday will largely be out of the Colts' control, as it will instead depend on his ability to pass through every stage of the concussion protocol. An absence would leave Nyheim Hines and Jordan Wilkins as the leaders of the Indianapolis backfield against a Jaguars defense that has given up just five touchdown to running backs all season. Jacksonville got the best of Mack in Week 10, limiting him to 29 yards on 12 carries and nine yards on two catches in a 29-26 Indianapolis victory.
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Chase Edmonds RB | WAS
Cardinals' Chase Edmonds: Ineffective in loss
Edmonds ran five times for zero yards during Sunday's 45-10 loss to the Chargers.
Edmonds also returned one kick for 13 yards. The rookie fourth-round pick's five carries tied a season high, but he was unable to make any sort of impact with his touches against the Chargers' revitalized run defense. He'll look to bounce back against the Packers in Week 13.
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: Considered week-to-week
Gordon (knee) will be evaluated on a week-to-week basis after Monday's MRI confirmed his initial diagnosis of an MCL sprain.
Ian Rapoport of NFL Network suggests the running back is expected to miss multiple games while recovering from a Grade 2 sprain. Given that the injury often carries a recovery timetable of 2-to-4 weeks, Gordon can safely be ruled out for Week 13 in Pittsburgh and may have a tough time making it back for Week 14 against the Bengals. A Thursday night matchup with the Chiefs in Week 15 won't help his odds of making the absence a short one, though it's still too soon to make assumptions about his status beyond the Pittsburgh game. Gordon's injury leaves Austin Ekeler as the lead dog in the Chargers backfield, with Justin Jackson and Detrez Newsome also in the mix for carries. Ekeler struggled as the fill-in starter Week 7 against Tennessee but has otherwise been uber-efficient in 27 career NFL games, averaging 5.7 yards on 117 carries and 10.7 yards on 59 receptions with nine total scores.
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Cordarrelle Patterson RB | PIT
Patriots' Cordarrelle Patterson: Logs 22 snaps
Patterson played 22 of the Patriots' 70 offensive snaps in Sunday's 27-13 win over the Jets and finished with one reception for minus-one yard and five carries for 10 yards.
Patterson's versatility and skills as a return man are useful to the Patriots, but his run of fantasy relevance seems to have come to a screeching halt following Sony Michel's return from injury in Week 11. The 27-year-old has earned a combined 10 touches the past two weeks and could see that number plunge further if the Patriots bring Rex Burkhead (concussion) back from injured reserve ahead of their Week 13 matchup with the Vikings.
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Jamaal Williams RB | NO
Packers' Jamaal Williams: Another quiet game
Williams had one carry for five yards in Sunday's 24-17 loss to the Vikings.
It was another quiet week for Williams, who was on the field for just 13 offensive snaps. Meanwhile, Aaron Jones played 40 snaps and had another productive outing (17 carries for 72 yards and a touchdown), so don't expect much to change with the Packers' backfield situation in Week 13 against the Cardinals.
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Jacquizz Rodgers RB | NO
Buccaneers' Jacquizz Rodgers: Solid complementary effort in win
Rodgers rushed five times for 31 yards and brought in four of five targets for 31 yards in the Buccaneers' 27-9 win over the 49ers on Sunday.
Rookie Ronald Jones (hamstring) was inactive once again, leaving Rodgers to serve as the primary backup to Peyton Barber. Rodgers was highly efficient on a per-touch basis, and the five carries he logged equaled a season high. The 28-year-old has been effective as a change-of-pace option over the last two games in particular, lending credence to the notion he could stick in his current role and potentially keep Jones inactive in the process. However, the relatively sparse usage he sees limits his fantasy utility to only the deepest of formats.
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Kenyan Drake RB | GB
Dolphins' Kenyan Drake: Practice work will be restricted
Drake is expected to be limited to non-contact work in practice this week after aggravating a left shoulder injury in Sunday's 27-24 loss to the Colts, Armando Salguero of the Miami Herald reports.
Drake played 24 of the Dolphins' 53 offensive snaps in Week 12, reaching the end zone twice and totaling 96 yards from scrimmage on 13 touches (eight carries, five receptions). The running back exited the contest briefly after a hard fall on the shoulder, but he was able to return to action before the game concluded. The Dolphins' plan to withhold Drake from contact in practices for the second straight week looks to be a safeguard more than anything, as the early expectation is that the 24-year-old will be able to work in tandem with Frank Gore as usual next weekend against the Bills.
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Ezekiel Elliott RB | LAC
Cowboys' Ezekiel Elliott: Dealing with sore hip
Elliott was held out of practice Sunday to rest a sore hip but was back on the field Monday with his teammates, Kate Hairopoulos of The Dallas Morning News reports.
Elliott apparently got a bit banged up in the 31-23 win over Washington on Thanksgiving Day, though the hip issue didn't prevent him from piling up 143 yards and a score on 31 touches. He may be listed as a limited participant when the Cowboys release their initial practice report for Week 13 in advance of Thursday's difficult matchup with the Saints. Dallas also has some injury concerns on the offensive line, which could be problematic against a New Orleans defense ranked first in rushing yards allowed (73.2 per game) and second in yards per carry (3.6) this season.
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: Likely facing multi-game absence
Gordon (knee) was diagnosed with a Grade 2 MCL sprain following Sunday's 45-10 win over the Cardinals and is expected to miss multiple games, Ian Rapoport of NFL Network reports.
The Chargers haven't confirmed Rapoport's report, but if Gordon is in fact dealing with a second-degree sprain, he'll likely need several weeks to recover from the injury. That puts his availability for at least Sunday's game against the Steelers in major jeopardy, though Rapoport notes the Chargers anticipate Gordon will be back to full strength before the postseason. In any event, Gordon's shaky health makes Austin Ekeler a must-add option in any fantasy league where he's still available. Justin Jackson could also see a slight bump in usage behind Ekeler, as was the case when Gordon sat out the Chargers' Week 7 win over the Titans in London.
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Matt Dayes RB | NO
49ers' Matt Dayes: Doesn't see field in loss
Dayes did not record a touch in Sunday's 27-9 loss to Tampa Bay.
Dayes was recently promoted from the practice squad along with fellow running back Jeff Wilson, but it was the latter who occupied Alfred Morris' (healthy scratch) backup role behind Matt Breida. There isn't much to see here from a fantasy perspective so long as Dayes remains third on the depth chart.