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Ben VanSumeren RB | KC
Chiefs' Ben VanSumeren: Elevated for season opener
The Chiefs elevated VanSumeren from the practice squad ahead of Monday's game against the Broncos.
VanSumeren was unable to win a roster spot with the Bills following training camp and the preseason, but he caught on with the Chiefs' practice squad after getting cut and will now get bumped up to the roster ahead of the season opener. If active for Monday's contest, VanSumeren will likely serve as a blocker on offense and be part of the Chiefs' special-teams units.
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Jordan Mason RB | MIN
Vikings' Jordan Mason: Nursing sore thumb after Week 1
Vikings head coach Kevin O'Connell said Monday that Mason is being further evaluated after experiencing thumb soreness coming out of Sunday's 39-22 win over the Packers, Alec Lewis of The Athletic reports.
Mason (30 of 65 offensive snaps) and Aaron Jones (29 snaps) had a near-even split of the backfield reps in Week 1, with the former leading the ground attack with 59 yards and a touchdown on 15 carries while going without a target. The 27-year-old apparently hurt his thumb at some point during the contest, but the Vikings haven't yet indicated that the injury is anything more than a day-to-day concern. Mason will likely be put through more tests before the Vikings have a clearer picture of his status heading into a Week 2 matchup with the Bears.
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Dylan Sampson RB | CLE
Browns' Dylan Sampson: Knee injury still being evaluated
Coach Todd Monken said Monday the team is still evaluating the severity of Sampson's knee injury, Daniel Oyefusi of ESPN.com reports.
Monken said more information will be known Wednesday, which would suggest he's playing coy since the Browns aren't required to provide any update until an injury report needs to be released Wednesday. Sampson was on crutches after Sunday's loss to the Jaguars, so he's likely looking at some missed time at least. Quinshon Judkins and Raheim Sanders handled backfield duties with Sampson sidelined.
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TreVeyon Henderson RB | NE
Patriots' TreVeyon Henderson: Returning to practice Monday
Coach Mike Vrabel said Henderson (ankle) will practice Monday, Mike Reiss of ESPN.com reports.
Henderson missed practice all last week leading up to Wednesday's season-opening loss to the Seahawks, but he's now had an additional four days to recover and appears to have a good chance to make his 2026 debut Sunday against the Steelers. Rhamondre Stevenson slogged his way to 2.8 yards per carry in Week 1 against Seattle, while Corey Kiner filled in as the RB2 and rushed for 11 yards on six carries.
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Cam Skattebo RB | NYG
Giants' Cam Skattebo: Opens scoring in Week 1 win
Skattebo rushed 18 times for 81 yards and a touchdown but wasn't targeted in the passing game during Sunday's 28-20 win over the Cowboys.
Skattebo opened the scoring with a three-yard touchdown run to cap the Giants' first possession of the season. The 2025 fourth-round pick looked spry in his return from a season-ending ankle fracture suffered in Week 8 of his rookie campaign. He led the team in both rushing attempts and rushing yards Sunday while Devin Singletary and Tyrone Tracy combined for just 30 rushing yards on eight carries, though Singletary got all four targets among Giants running backs and scored a fourth-quarter receiving touchdown. Skattebo should continue to spearhead the Giants' rushing attack in Week 2 against the Rams on Monday Night Football.
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Javonte Williams RB | DAL
Cowboys' Javonte Williams: Scores twice in Week 1 loss
Williams rushed 12 times for 41 yards and a touchdown while catching all five of his targets for 31 yards and a touchdown in Sunday's 28-20 loss to the Giants.
Williams scored a one-yard rushing touchdown in the third quarter and added a 17-yard touchdown catch in the fourth quarter. He was called for a 15-yard taunting penalty on his touchdown catch, and Brandon Aubrey missed the ensuing PAT to keep Dallas' deficit at eight points with 5:21 remaining, though that miss proved moot after the Giants proceeded to eat up the remainder of the game clock on the ensuing possession. No Cowboys teammate had more than two carries in Sunday's loss, so Williams is locked in as the primary option in Dallas' backfield heading into a Week 2 home game against the Commanders.
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Samaje Perine RB | CIN
Bengals' Samaje Perine: Efficient in Week 1 win
Perine rushed five times for 20 yards and caught all three targets for 30 yards in a 33-27 win over Tampa Bay on Sunday.
Perine was the only Bengals running back besides starter Chase Brown (16-56-1 rushing line) to record a carry, and the former also finished with Cincinnati's third-highest receiving yardage total. Perine fell off quite a bit as a pass catcher last year, finishing with just 17 receptions for 87 yards over 15 games, so his usage in that capacity Sunday was promising in terms of his potential fantasy value. The Bengals next make a trip to Houston, and though the Texans were one of the league's best defenses last year, they gave up 409 total yards to Buffalo on Sunday.
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Tyler Allgeier RB | ARI
Cardinals' Tyler Allgeier: Robust workload in Week 1 win
Allgeier rushed 17 times for 61 yards and brought in both targets for nine yards in the Cardinals' 26-14 win over the Chargers on Sunday.
Allgeier lived up to his No. 1 slotting on the Week 1 depth chart, outpacing Jeremiyah Love by six carries and matching the rookie's reception total, albeit on two fewer targets. Allgeier did scuffle for rushing yards all afternoon long, but the veteran back helped keep the Chargers defense honest and proved capable of leading the ground attack. Love should be in line for a progressive boost in volume as the season unfolds, and there's no doubt as to which player between him and Allgeier has the higher ceiling; nevertheless, the latter should continue to see plenty of opportunity during a Week 2 home divisional clash with the defending champion Seahawks next Sunday.
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Keaton Mitchell RB | LAC
Chargers' Keaton Mitchell: Unimpressive in Chargers debut
Mitchell rushed four times for nine yards in a Week 1 loss to Arizona on Sunday. He added 47 yards on two kickoff returns.
Mitchell had a long rush of eight yards but combined for just three yards on his other three carries. While he also contributed in the return game, it was a bland Chargers debut for the 24-year-old, who joined Los Angeles as a free agent in March. The Chargers' run game as a whole was largely stifled Sunday, as Omarion Hampton -- the only other RB on the team to log a carry -- finished with a mediocre 43 yards on 12 carries, though he did score a touchdown. Mitchell will look to make more of an impression in Week 2 versus Las Vegas next Sunday.
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Ray Davis RB | BUF
Bills' Ray Davis: Handles one touch in Week 1
Davis rushed one time for three yards in Buffalo's 36-31 win over the Texans on Sunday.
Frank Gore actually out-snapped Davis 10-5 behind James Cook, as both Davis and Gore rushed one time for three yards. If something were to ever happen to Cook, it looks like Gore could actually have a bigger role than expected, making Davis a shakier bench stash in fantasy.