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Jerry Jeudy WR | CLE
Browns' Jerry Jeudy: Limited in practice Wednesday
Jeudy (knee) was a limited participant in Wednesday's practice, Mary Kay Cabot of The Cleveland Plain Dealer reports.
Jeudy is listed on Cleveland's injury report for the first time this year, though the fact that he was able to practice on at least a limited basis provides reason for optimism that he'll be able to gain clearance for Sunday's matchup against the Dolphins. Still, Jeudy has struggled notably with efficiency across two appearances with quarterback Dillon Gabriel under center, having totaled seven grabs for 58 yards (on 18 targets) in that span. Even if he's able to resume practicing in full and avoid an injury designation entirely for Week 7, fantasy managers may be motivated to pursue an option at the wide receiver position that has demonstrated greater upside. Across six regular-season appearances so far Jeudy has yet to score a touchdown, and he hasn't surpassed 50 receiving yards since Week 2.
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Travis Vokolek TE | ARI
Cardinals' Travis Vokolek: Done for the year
The Cardinals placed Vokolek on injured reserve Wednesday due to a season-ending neck injury, Darren Urban of the team's official site reports.
Vokolek was carted off the field during Arizona's loss to the Colts in Week 6 due to a neck injury and concussion suffered during kickoff coverage. He was evaluated at a local hospital before being released the same day, but head coach Jonathan Gannon confirmed that the third-year tight end won't be a candidate to return to action this season. Vokolek suited up for a career-high five regular-season games with Arizona in 2025, though he wasn't targeted on offense.
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Jalin Hyatt WR | NYG
Giants' Jalin Hyatt: Dealing with ankle issue
Hyatt was limited at Wednesday's practice due to an ankle injury, Dan Salomone of the Giants' official site reports.
Hyatt has settled into a modest role in New York's offense over the last three games, but it took him until last Thursday's win against the Eagles to make a mark in the box score (3-17-0 on five targets). With Malik Nabers (knee) out for the season and Darius Slayton (hamstring) still not practicing, Hyatt is lined up to be involved on game days, assuming he makes it through Week 7 prep unscathed.
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Darren Waller TE | CAR
Dolphins' Darren Waller: Limited Wednesday
Waller (hip/rest) was limited in practice Wednesday, Scott Petrak of the Elyria Chronicle-Telegram reports.
Waller continues to have his practice reps capped due to a load management plan, though his gameday workload has now increased in three consecutive weeks. The veteran tight end handled a season-high 69 percent of offensive snaps during Miami's loss to the Chargers in Week 6, securing two of three targets for 12 yards and a touchdown. Waller has scored in all three of his appearances with the Dolphins this season. He'll face a challenge to keep up that streak on the road against the Browns' vaunted defense on Sunday, though if Cleveland's pass rush forces Tua Tagovailoa to rely heavily on short-area passes, it could result in increased target volume for Waller.
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Mac Jones QB | SF
49ers' Mac Jones: Limited Wednesday
Coach Kyle Shanahan said Jones (knee/oblique) will be limited at practice Wednesday, Cam Inman of The San Jose Mercury News reports.
Jones will be joined on the practice field by No. 1 QB Brock Purdy (toe), though the latter will be more limited than the former, according to what Shanahan told Matt Barrows of The Athletic. It's unknown if that means Jones has better odds than Purdy to continue leading the 49ers offense Week 7, but Purdy at least has put himself in a position to see his first game action since Week 4. In four starts in place of Purdy this season, Jones has completed 113 of 168 passes (67.3 percent) for 1,252 yards, six touchdowns and three interceptions, rushed 16 times for 23 yards and fumbled three times (one lost).
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Skyy Moore WR | GB
49ers' Skyy Moore: Absent from practice
San Francisco coach Kyle Shanahan said Wednesday that Moore (ankle) is not practicing, Cam Inman of The San Jose Mercury News reports.
Moore appears to have sustained an ankle injury during the 49ers' loss to Tampa Bay in Week 6, making him uncertain for Sunday's contest against the Falcons. He hasn't logged a target on offense in back-to-back games, though Moore did compile a season-best 109 yards as a kick returner versus the Buccaneers, plus 25 yards as a punt returner. He remains off the fantasy radar in all formats other than deeper leagues that place a premium on return yardage.
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Josh Downs WR | IND
Colts' Josh Downs: In concussion protocol
Downs (concussion) didn't practice Wednesday.
With Downs in the NFL's concussion protocol, per Stephen Holder of ESPN.com, the wideout's status will need to be tracked ahead of this weekend's game against the Chargers. In this past Sunday's 31-27 win over the Cardinals, Downs logged a 51 percent snap share while catching six of his seven targets for 42 yards and a touchdown. If he's limited or out versus Los Angles, Ashton Dulin (chest) -- if available -- Adonai Mitchell and Anthony Gould would be candidates for added snaps alongside fellow WRs Michael Pittman and Alec Pierce.
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George Kittle TE | SF
49ers' George Kittle: Limited in return to practice
Head coach Kyle Shanahan said Kittle (hamstring) will be a limited participant at Wednesday's practice, thereby designating the tight end to return from injured reserve, Cam Inman of The San Jose Mercury News reports.
Last Wednesday, Shanahan told David Lombardi of SFStandard.com that Kittle as a chance to suit up Week 7, and the tight end's return to practice this Wednesday is the first step in making that a reality. Kittle has been sidelined since the season opener, when he injured his hamstring in the first half of an eventual 49ers win at Seattle. Ultimately, Friday's practice report will reveal his odds to play Sunday versus the Falcons.
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Ricky Pearsall WR | SF
49ers' Ricky Pearsall: Unable to practice Wednesday
San Francisco coach Kyle Shanahan said Pearsall (knee) will not practice Wednesday, Cam Inman of The San Jose Mercury News reports.
Shanahan said Monday that Pearsall would be evaluated Wednesday to determine his practice level for Week 7, so the 2024 first-round pick's lack of participation could be a sign that he isn't yet nearing a return to on-field reps. Meanwhile, QB Brock Purdy (toe), TE George Kittle (hamstring) and WR Jauan Jennings (ribs) all practiced in a limited capacity Wednesday, and all three appear to have a chance at playing Sunday versus the Falcons. Kittle remains on IR for the time being, however, while Jennings played through five broken ribs during San Francisco's loss to the Buccaneers in Week 6.
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Deebo Samuel WR | SF
Commanders' Deebo Samuel: Listed as non-participant
Samuel (heel) is listed as a non-participant on Wednesday's practice report.
He played through the same injury the past two games, putting up an 8-96-1 receiving line in Week 5 before slumping to 4-15-0 in Week 6. Samuel topped a 70 percent snap share in both games, but the Commanders might ease up on his workload some if the heel continues to give him trouble and WR Terry McLaurin (quad) is available to pick up slack. McLaurin is returning to practice this week, but it isn't yet clear if he'll be ready for Sunday's game at Dallas. Samuel also needs to be monitored, and there will be serious concern if he doesn't return to practice by Friday.