NFL Player News

Pearsall (knee) is listed as active Sunday against the Jaguars, Briana Jeannel of the 49ers' official site reports.

A knee injury hampered Pearsall in practice during Week 4 prep, resulting in a DNP on Wednesday and limited sessions Thursday and Friday. On Wednesday, the second-year pro told Jennifer Lee Chan of NBC Sports Bay Area that he'd play that day if there was a game, and now that Sunday has arrived, he'll be out there as he normally is for the 49ers offense. Considering fellow WR Jauan Jennings (ankle/shoulder) reportedly will have his snaps monitored, per Adam Schefter of ESPN, Pearsall is lined up to be Brock Purdy's (left shoulder/toe) top pass catcher in the quarterback's return to action.

Brown (shoulder) is inactive for Sunday's game against the 49ers.

Brown, who exited the Jaguars' 17-10 win over the Texans in Week 3 after recording 23 snaps and two catches for seven yards on three targets, approached the contest listed as questionable after practicing in a limited fashion Thursday and Friday. In his absence Sunday, Brian Thomas, Travis Hunter and Parker Washington are on track to lead the Jaguars' wideout corps versus San Francisco, with Washington (who saw 11 targets in Week 3) representing a lineup pivot for those scrambling for help at the WR position in Week 4.

Jennings (ankle/shoulder) is active for Sunday's game versus the Jaguars, Briana Jeannel of the 49ers' official site reports.

Jennings was gutting out a shoulder injury in the later stages of Week 1 and all of Week 2, but in the latter contest, he picked up an ankle injury that sidelined him Week 3 and didn't allow him to practice until Friday in a limited capacity. While he'll be available to the 49ers offense Sunday, there's an expectation that his snaps will be monitored, per Adam Schefter of ESPN. As a result, managers may want to pivot to a healthier option until Jennings is able to handle a typical workload, even with QB Brock Purdy (left shoulder/toe) back in action.

Adams (hamstring) is active for Sunday's Week 4 game against the Colts, Sarah Barshop of ESPN.com reports.

The veteran wideout was able to get in a limited practice Friday after sitting out the first two sessions of the week, and Adams has now validated head coach Sean McVay's optimism that he'd be able to suit up and fill his usual No. 2 role against Indianapolis. Adams thus has far proven an ideal complementary fit in the Rams' air attack alongside No. 1 receiver Puka Nacua, posting a 13-213-2 line on 29 targets through his first three contests.

Buckner (back) is active for Sunday's game against the Rams.

A back injury limited Buckner's practice participation this past week, but he has been cleared to play in Sunday's road game. The veteran defensive lineman has registered 14 tackles (nine solo) through the first three games of the regular season.

Jackson is questionable to return to Sunday's game against the Patriots due to a knee injury, Darin Gantt of the Panthers' official site reports.

Jackson was able to walk off the field under his own power, and he'll have his knee injury monitored by medical staff to determine whether he can return. The Panthers would be down to just four defensive linemen if Jackson is unable to play, with Tershawn Wharton serving in rotation behind A'Shawn Robinson, Bobby Brown and Derrick Brown.

Joseph is questionable to return to Sunday's game against the Browns due to a knee injury.

Joseph appeared to injure his knee on the same play that D.J. Reed picked off Joe Flacco in the second quarter. Joseph was helped off the field by two trainers to avoid putting pressure on his leg before being taken to the locker room, per Colton Pouncy of The Athletic. Thomas Harper will likely see more snaps at safety alongside Brian Branch for as long as Joseph is sidelined.

Tillman won't return to Sunday's game against the Lions after sustaining a hamstring injury.

Tillman approached the contest without an injury designation after being limited Wednesday and Thursday by listed hand and hip issues, so Sunday's hamstring injury is something new for the wideout. Prior to his exit, Tillman caught one of his two targets for six yards. In his absence, Isaiah Bond, Jamari Thrash and DeAndre Carter are available to handle WR snaps that don't go to Jerry Jeudy.

Nabers was carted to the locker room due to an apparent right knee injury during Sunday's game against the Chargers, Dan Duggan of The Athletic reports.

Nabers stayed down on the ground while grabbing at his knee after he attempted to make a leaping grab down the sideline. Considering he needed a cart to leave the field, there's a decent chance his Week 4 is over.

Holland is questionable to return to Sunday's game against the Chargers due to a neck injury, Dan Salomone of the Giants' official site reports.

It's unclear when Holland suffered the neck injury, but he will be monitored by trainers to determine whether he can return. With Beau Brade (coach's decision) inactive, Dane Belton will see increased snaps at safety alongside Tyler Nubin for as long as Holland is out of the game.