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Yetur Gross-Matos DE | SF
49ers' Yetur Gross-Matos: Working through knee issue
Gross-Matos (knee) did not participate in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.
Gross-Matos opened training camp on the active/PUP list due to what was reported at the time as an undisclosed issue. He's no longer on the PUP list, but Wednesday's practice report revealed that the 2020 second-rounder has been working through a knee injury. Gross-Matos would need to return to practice in at least a limited capacity over the next two days to have a chance at playing in Sunday's regular-season opener against Seattle.
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Dareke Young WR | LV
Seahawks' Dareke Young: Limited participant in practice
Young (hamstring) was a limited participant in Seattle's practice Wednesday, John Boyle of the team's official site reports.
Young's status for Sunday's season opener against the 49ers is now up in the air after he popped up on the team's injury report Wednesday. His availability in practice Thursday and Friday will provide more clarity on whether the 26-year-old will be able to suit up versus San Francisco.
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Chauncey Gardner-Johnson SAF | BUF
Texans' C.J. Gardner-Johnson: Healthy ahead of Week 1
Gardner-Johnson (knee) did not appear on the Texans' injury report Wednesday.
Gardner-Johnson suffered a knee injury in early August, but he avoided any major damage and will now be active for the team's regular-season opener against the Rams on Sunday. The 27-year-old is expected to operate as Houston's starting free safety in 2025.
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CJ West DT | SF
49ers' CJ West: Logs full practice Wednesday
West (knee) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.
The rookie fourth-rounder hyper-extended his knee in mid-August, which prevented him from playing in the 49ers' final two preseason games. West was able to open the week with a full practice, which puts him on track to play in Sunday's regular-season opener against the Seahawks. He's expected to serve in a rotational role at defensive tackle with Alfred Collins, Kalia Davis and Jordan Elliott.
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Upton Stout CB | SF
49ers' Upton Stout: Recovered from calf injury
Stout (calf) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.
A calf injury prevented Stout from playing in any of San Francisco's preseason games. However, his full participation in Wednesday's practice indicates that the rookie-third rounder has recovered from the injury and is on track to play in Sunday's regular-season opener against Seattle. Stout should see a significant amount of playing time in the secondary with the 49ers' first-team defense alongside Deommodore Lenoir, Renardo Green, Ji'Ayir Brown and Jason Pinnock.
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Mykel Williams DE | SF
49ers' Mykel Williams: Full participant in practice
Williams (knee) practiced in full Wednesday, Cam Inman of The San Jose Mercury News reports.
The rookie first-rounder ended up missing all three of the 49ers' preseason games due to a knee injury that he suffered in early August. Williams was able to log a full practice to open the week, indicating that he is on track to make his NFL regular-season debut against the Seahawks on Sunday. He's expected to see a prominent role on the 49ers' defensive front alongside Nick Bosa, Kalia Davis and Jordan Elliott.
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Jason Pinnock SAF | NYG
49ers' Jason Pinnock: Logs full practice
Pinnock (heel) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.
Pinnock did not play in the Niners' last two preseason games due to a lingering heel injury, but he appears to be past the issue and on track to play against the Seahawks on Sunday. With Malik Mustapha (knee) beginning the season on the reserve/PUP list, Pinnock is slated to serve in a starting role at safety alongside Ji'Ayir Brown.
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Jordan Howden SAF | NO
Saints' Jordan Howden: Limited in practice
Howden (oblique) was a limited participant in New Orleans' practice Wednesday.
Howden popped up on the injury report, leaving his status for Sunday's season opener versus the Cardinals up in the air. Once healthy, the 25-year-old is expected to serve as the team's backup strong safety behind Justin Reid and he likely will contribute on special teams as well.
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Deommodore Lenoir CB | SF
49ers' Deommodore Lenoir: Recovered from hip injury
Lenoir (hip) was not listed on the 49er's injury report Wednesday, Cam Inman of The San Jose Mercury News reports.
Lenoir was limited to just one preseason game due to a lingering hip injury that popped up in late July. He appears to be over the issue and is in line to suit up for Sunday's regular-season opener against Seattle. The 2021 fifth-rounder is expected to step up as the 49ers' top CB after Charvarius Ward signed with the Colts during the offseason.
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Nick Bosa DE | SF
49ers' Nick Bosa: Fades injury report
Bosa (neck) was not listed on Wednesday's injury report, Cam Inman of The San Jose Mercury News reports.
Neck soreness limited Bosa's practice participation during training camp. He appears to be past the issue and will have a clean bill of health entering Sunday's regular-season opener against the Seahawks. Bosa logged 52 tackles (33 solo), including 9.0 sacks, one interception, one forced fumble and one fumble recovery across 14 regular-season games in 2024.