West (knee) was a limited participant in Wednesday's practice, Matt Barrows of The Athletic reports.
The 49ers opened West's 21-day practice window open Wednesday, and he was limited in his return to on-field practice. He landed on injured reserve in late September due to a knee injury, and he would need to be activated from IR in order to be available for Sunday's road game against the Cowboys.
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49ers' C.J. West: Nearing return
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The 49ers plan to open West's (undisclosed) practice window Wednesday, David Lombardi of SFStandard.com reports.
West was placed on injured reserve in late September due to an undisclosed injury but is now nearing his return. Once the practice window is officially opened, San Francisco will have 21 days to activate the 2025 fourth-round pick, or else he'll be forced to stay on injured reserve for the remainder of the campaign.
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49ers' CJ West: Placed on injured reserve
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The 49ers placed West (undisclosed) on injured reserve Wednesday.
It remains unclear what issue is sidelining the second-year player. West will now need to miss at least four games on IR before becoming eligible to return to the active roster. The defensive tackle has logged five tackles (one solo) over 49 defensive snaps in the 49ers' first two regular-season games.
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49ers' CJ West: Earns first career sack
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West appeared in 14 games for the 49ers in 2025, finishing the regular season with 21 tackles (12 solo) and one sack.
The fourth-round draft pick was eased into the defensive line rotation before watching his snap count rise in the second half of the schedule. West nabbed his first career sack in Week 16 of the regular season and then went on to record another in the 49ers' divisional round loss to the Seahawks. The 23-year-old will enter his second pro season with an opportunity to compete for a starting defensive tackle position.
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49ers' CJ West: Good to go Week 5
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West (thumb) is active for Thursday's game against the Rams, Briana Jeannel of the 49ers' official site reports.
West underwent surgery to repair a thumb injury that he sustained during the 49ers' Week 3 win over the Cardinals. He was unable to play against the Jaguars on Sunday, but the rookie fourth-rounder has been cleared to play in Thursday's road tilt. West has two tackles (one solo) through the first three regular-season games of his NFL career.
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49ers' CJ West: Unavailable for Week 4
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West (thumb) has been ruled out for Sunday's contest against Jacksonville.
West suffered a broken thumb in Week 3 against the Cardinals, and he's expected to require surgery to address it. In his absence, Alfred Collins and Jordan Jefferson stand to see an increase in workload at defensive tackle behind starters Kalia Davis and Jordan Elliott versus the Jaguars.
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49ers' CJ West: Logs full practice Wednesday
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West (knee) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.
The rookie fourth-rounder hyper-extended his knee in mid-August, which prevented him from playing in the 49ers' final two preseason games. West was able to open the week with a full practice, which puts him on track to play in Sunday's regular-season opener against the Seahawks. He's expected to serve in a rotational role at defensive tackle with Alfred Collins, Kalia Davis and Jordan Elliott.
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49ers' CJ West: Hyperextends knee
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West has a hyperextended knee, David Lombardi of the San Francisco Standard reports.
West's likely looking at a short-term injury, per Lombardi, though a more specific recovery timeline hasn't been established for the rookie fourth-round pick. The 49ers begin regular-season play Sept. 7 against the Seahawks. San Francisco's next preseason game is Saturday against the Raiders.
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49ers' CJ West: More defensive line help in SF
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The 49ers selected West in the fourth round of the 2025 NFL Draft, 113th overall.
The 49ers have prioritized the defensive line in this draft and add another big body in West to go with Alfred Collins from the second round. West (6-foot-1, 316 pounds) has good quickness for his size and can collapse a pocket with his violent hands. Starting out at Kent State, West finished at Indiana and showed he could move up a weight class and still produce, as he was a big part of a Hoosier team that made an amazing run to the College Football Playoff.