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Dee Winters LB | DAL
49ers' Dee Winters: Cleared to play Thursday
Winters (knee) doesn't carry an injury designation into Thursday night's game against the Rams, Matt Barrows of The Athletic reports.
Winters played 100 percent of the defensive snaps last Sunday against the Jaguars but was limited in early-week practices before being cleared to play against Los Angeles. Winters has started all four games at linebacker for the Niners, logging 32 tackles (24 solo), including three TFLs, and two pass breakups on over 99 percent of the defensive snaps.
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Juwan Johnson TE | NO
Saints' Juwan Johnson: DNP due to ankle issue
Johnson missed Wednesday's practice due to an ankle injury
This marks the first time this season that Johnson's practice reps have been impacted in any way, while fellow TEs Taysom Hill (knee, reserve/PUP list) and Foster Moreau (knee, reserve/PUP list), who had their practice windows opened this week, were both limited. It remains to be seen if Johnson's status is in peril for Sunday's game against the Giants, but he at least will have two more chances to mix into drills this week before the Saints potentially make a ruling on his availability for Week 5.
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Jordan Watkins WR | SF
49ers' Jordan Watkins: Ruled out for TNF
Watkins (calf) has been ruled out for Thursday night's game against the Rams, Matt Barrows of The Athletic reports.
Selected in the fourth round of the 2025 Draft back in April, Watkins is still waiting to make his regular-season NFL debut. He suffered a high ankle sprain back in August and is now dealing with a calf issue. With all the injuries San Francisco is dealing with at wide receiver, Watkins is missing a big opportunity to play.
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Calvin Ridley WR | TEN
Titans' Calvin Ridley: Sits out practice Wednesday
Ridley (knee/elbow) didn't practice Wednesday, Jim Wyatt of the Titans' official site reports.
Coach Brian Callahan revealed Monday that Ridley played through an injury in Sunday's 26-0 loss to the Texans, en route to logging a season-low 54 percent snap share. Now we know that the wideout is managing knee and elbow issues ahead of this weekend's game against the Cardinals. Ridley has two more chances to practice before the Titans' Week 5 injury designations are posted Friday. If he's limited or out versus Arizona, Tyler Lockett, Chimere Dike and Van Jefferson would be candidates for added snaps alongside Elic Ayomanor.
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Miles Sanders RB | DAL
Cowboys' Miles Sanders: Doesn't practice Wednesday
Sanders (knee/ankle) was a non-participant at Wednesday's practice, Nick Harris of the Fort Worth Star-Telegram reports.
Sanders exited this past Sunday's tie with the Packers just before halftime due to an ankle injury, but coach Brian Schottenheimer told Joe Hoyt of The Dallas Morning News on Monday that the running back was trending toward being able to play Week 5 at the Jets. On Wednesday, Sanders himself said he had an MRI on his right ankle, and the Cowboys will have a better idea of his upcoming availability, or lack thereof, if he's able to run by Friday, according to Calvin Watkins of The Dallas Morning News. As such, Sanders' status will be monitored as the week goes on to see if he'll be able to continue in his complementary role behind Javonte Williams on Sunday.
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Tyjae Spears RB | TEN
Titans' Tyjae Spears: Limited in return to practice
Spears (ankle) was officially limited in Wednesday's practice, Jim Wyatt of the Titans' official site reports.
The Titans officially moved Spears to the designated-to-return-to-practice list Wednesday, so it's unsurprising to see him with a cap on his activity level as he practices for the first time since suffering a high-ankle sprain in August. Per John Glennon of NashvillePost.com, Spears said he's taking it one day at a time in regards to the possibility of his playing Sunday against Arizona. Before being eligible to suit up, Tennessee will have to officially activate Spears from IR. At that point, he'll join Tony Pollard atop the team's backfield.
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CeeDee Lamb WR | DAL
Cowboys' CeeDee Lamb: Still sidelined at practice
Lamb (ankle) officially didn't take part in Wednesday's practice, Nick Harris of the Fort Worth Star-Telegram reports.
On a positive note, Lamb ditched his walking boot and resumed on-field work Wednesday, specifically with resistance bands, per Clarence Hill Jr. of AllDLLS.com. Prior to the session, coach Brian Schottenheimer told Jon Machota of The Athletic that Lamb is "progressing well" in his recovery from the high left-ankle sprain that he sustained during a Week 3 loss in Chicago, but the Cowboys also will "see how the week goes" before making a call on his Week 5 status. Lamb likely will need to mix into some drills Thursday and/or Friday in order to put himself in a position to return to action, but the Cowboys' final injury report of the week may provide some clarity on that front.
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D.J. Reed CB | DET
Lions' D.J. Reed: Sent to injured reserve
The Lions placed Reed (hamstring) on injured reserve Wednesday.
Reed was injured in last Sunday's win over the Browns and will now miss a minimum of four games. Currently, Rock Ya-Sin, Amik Robertson and Avonte Maddox are the Lions' only healthy cornerbacks, as Terrion Arnold (shoulder) and Khalil Dorsey (concussion) are also banged up. Reed will be eligible to return in Week 9 against the Commanders.
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KaVontae Turpin WR | DAL
Cowboys' KaVontae Turpin: Officially DNP on Wednesday
Turpin (foot) was a non-participant in Wednesday's practice, Nick Harris of the Fort Worth Star-Telegram reports.
Turpin wasn't spotted at the early portion of Wednesday's practice, and now his lack of activity has been confirmed. The No. 4 receiver and standout return man is nursing a foot injury sustained during the Cowboys' overtime tie against the Packers in Week 4. He'll have two more opportunities to mix into drills ahead of Sunday's game against the Jets.
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Myles Garrett LB | LAR
Browns' Myles Garrett: Absent from practice Wednesday
Garrett (ankle) did not practice Wednesday, Chris Easterling of the Akron Beacon Journal reports.
Garrett has been labeled as day-to-day by coach Kevin Stefanski, Ashley Bastock of The Cleveland Plain Dealer reports, and the veteran edge rusher isn't someone who needs to practice during the week in order to play on Sunday.